Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2082581..2082726 Replicon chromosome
Accession NZ_CP068797
Organism Klebsiella pneumoniae strain RIVM_C014073

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2082617..2082719 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2082581..2082726 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN67_RS10290 2077711..2079771 + 2061 WP_032419805.1 oligopeptidase B -
JNN67_RS10295 2079775..2080434 - 660 WP_100097888.1 exodeoxyribonuclease X -
JNN67_RS10300 2080513..2080743 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JNN67_RS10305 2080856..2081230 + 375 WP_020316569.1 CopC domain-containing protein YobA -
JNN67_RS10310 2081234..2082103 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JNN67_RS10315 2082120..2082458 + 339 WP_002911404.1 YebY family protein -
- 2082581..2082726 - 146 - - Antitoxin
- 2082617..2082719 + 103 - - Toxin
JNN67_RS10320 2083094..2083237 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JNN67_RS10325 2083342..2084310 - 969 WP_014907334.1 VirK/YbjX family protein -
JNN67_RS10330 2084467..2085120 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
JNN67_RS10335 2085117..2085308 - 192 WP_002911395.1 YebW family protein -
JNN67_RS10340 2085406..2085645 - 240 WP_002911393.1 YebV family protein -
JNN67_RS10345 2085761..2087194 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2012685..2087149 74464


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T187762 NZ_CP068797:2082617-2082719 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT187762 NZ_CP068797:c2082726-2082581 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References