Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2287570..2287841 Replicon chromosome
Accession NZ_CP068796
Organism Escherichia coli strain RIVM_C012087

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2287700..2287803 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2287570..2287841 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN38_RS11025 2284125..2284787 - 663 WP_000944256.1 exodeoxyribonuclease X -
JNN38_RS11030 2284811..2285467 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
JNN38_RS11035 2285569..2285799 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JNN38_RS11040 2285938..2286312 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JNN38_RS11045 2286316..2287188 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
JNN38_RS11050 2287201..2287542 + 342 WP_000976472.1 YebY family protein -
- 2287570..2287841 - 272 - - Antitoxin
- 2287700..2287803 + 104 - - Toxin
JNN38_RS11055 2287938..2288594 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
JNN38_RS11060 2288595..2288786 - 192 WP_001296140.1 YebW family protein -
JNN38_RS11065 2288891..2289127 - 237 WP_001295499.1 DUF1480 family protein -
JNN38_RS11070 2289245..2290684 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2265727..2303681 37954


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T187739 NZ_CP068796:2287700-2287803 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT187739 NZ_CP068796:c2287841-2287570 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References