Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2967142..2967773 Replicon chromosome
Accession NZ_CP068771
Organism Serratia plymuthica strain UBCF_13

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JK621_RS13775 Protein ID WP_212556486.1
Coordinates 2967142..2967540 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JK621_RS13780 Protein ID WP_212556487.1
Coordinates 2967540..2967773 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JK621_RS13750 (JK621_13750) 2962577..2962963 + 387 WP_212556481.1 type II toxin-antitoxin system RelE/ParE family toxin -
JK621_RS13755 (JK621_13755) 2962944..2963246 + 303 WP_212556482.1 DNA-binding transcriptional regulator -
JK621_RS13760 (JK621_13760) 2963385..2963789 - 405 WP_212556483.1 flagellar protein FlhE -
JK621_RS13765 (JK621_13765) 2963789..2965867 - 2079 WP_212556484.1 flagellar biosynthesis protein FlhA -
JK621_RS13770 (JK621_13770) 2965860..2967011 - 1152 WP_212556485.1 flagellar biosynthesis protein FlhB -
JK621_RS13775 (JK621_13775) 2967142..2967540 - 399 WP_212556486.1 type II toxin-antitoxin system VapC family toxin Toxin
JK621_RS13780 (JK621_13780) 2967540..2967773 - 234 WP_212556487.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JK621_RS13785 (JK621_13785) 2967899..2968543 - 645 WP_212556488.1 protein phosphatase CheZ -
JK621_RS13790 (JK621_13790) 2968554..2968943 - 390 WP_006326141.1 chemotaxis response regulator CheY -
JK621_RS13795 (JK621_13795) 2969160..2970209 - 1050 WP_212556489.1 chemotaxis response regulator protein-glutamate methylesterase -
JK621_RS13800 (JK621_13800) 2970209..2971081 - 873 WP_212556490.1 protein-glutamate O-methyltransferase CheR -
JK621_RS13805 (JK621_13805) 2971110..2972735 - 1626 WP_212556491.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-116)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14805.99 Da        Isoelectric Point: 6.9901

>T187699 WP_212556486.1 NZ_CP068771:c2967540-2967142 [Serratia plymuthica]
MFSHMLDTNIVIYVIKRRPLEVLEAFNRYAGKMVISSITYGELVHGVEKSSRPAVNARVVEDFVSRLDILDYGAKAASHY
GNIRAALERQGTPIGVNDLHIAGHARSEGLILVSNNMREFEPVEGLRLENWL

Download         Length: 399 bp

>T187699 NZ_CP089952:c4697534-4697400 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8776.69 Da        Isoelectric Point: 4.5680

>AT187699 WP_212556487.1 NZ_CP068771:c2967773-2967540 [Serratia plymuthica]
MTLGSVFTNNRTQAVRLPAEVRFPDSVSKVSVRVVGKERILSPVENTWDSFFCAENEVSDDFLNERAGQHQSEREDF

Download         Length: 234 bp

>AT187699 NZ_CP089952:c4697763-4697611 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References