187687

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 697377..697933 Replicon chromosome
Accession NZ_CP068771
Organism Serratia plymuthica strain UBCF_13

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JK621_RS03260 Protein ID WP_212558619.1
Coordinates 697377..697667 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JK621_RS03265 Protein ID WP_212558620.1
Coordinates 697655..697933 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JK621_RS03240 (JK621_03240) 692424..693374 - 951 WP_212558615.1 GNAT family N-acetyltransferase -
JK621_RS03245 (JK621_03245) 693371..695116 - 1746 WP_212558616.1 IucA/IucC family protein -
JK621_RS03250 (JK621_03250) 695254..696477 + 1224 WP_212558617.1 MFS transporter -
JK621_RS03255 (JK621_03255) 696483..697367 + 885 WP_212558618.1 siderophore-interacting protein -
JK621_RS03260 (JK621_03260) 697377..697667 - 291 WP_212558619.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JK621_RS03265 (JK621_03265) 697655..697933 - 279 WP_212558620.1 CopG family ribbon-helix-helix protein Antitoxin
JK621_RS03270 (JK621_03270) 698019..698405 - 387 WP_212558621.1 oxalurate catabolism protein HpxZ -
JK621_RS03275 (JK621_03275) 698409..699809 - 1401 WP_212558622.1 AtzE family amidohydrolase -
JK621_RS03280 (JK621_03280) 699806..699997 - 192 WP_006322394.1 oxalurate catabolism protein HpxX -
JK621_RS03285 (JK621_03285) 700022..701608 - 1587 WP_212558623.1 gamma-glutamyltransferase -
JK621_RS03290 (JK621_03290) 701877..702716 + 840 WP_212558624.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10837.50 Da        Isoelectric Point: 10.1818

>T187687 WP_212558619.1 NZ_CP068771:c697667-697377 [Serratia plymuthica]
VPQLIWTPAALLDVQRLYRFLAEKDLNSAKRAVAAIRNSIKIIAHQPNTGRPAKDMAPEFREWPVDFGNSGYLVLYRFNG
VTAVILAIRHQSETGY

Download         Length: 291 bp

>T187687 NZ_CP089943:17163-17450 [Erwinia tracheiphila]
ATGACCTATCGGGTGAAGTTCAGAACGGATGCGCTGAAAGAATGGAATAATCTTGATAAAGCTATTCAGCAGCAGTTTGT
CCGGAAGCTAAAGAAATGTGCGGAGAATCCTCATATCCCTTCCGCAAAGTTACGAGGAATGCCCGATTGCTATAAAATCA
AACTGCAAGCATCGGGCTTCAGGCTGGTTTATCAGGTTATTAACGACGAACTCATCATTGCTGTGGTCGCTGTAGGCAAA
CGTGAGCACAGCAAAGTTTATAATCTGGCCAGCAAACGGCTAAGATAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10632.69 Da        Isoelectric Point: 4.7494

>AT187687 WP_212558620.1 NZ_CP068771:c697933-697655 [Serratia plymuthica]
MATATSIKIDDELKQRVQHIAATQQRSAHWIMREAIREYVEREEKREAVRNDALQAWETYQANGKHLTQDEADGWLADLE
KGDDTEIPGCHN

Download         Length: 279 bp

>AT187687 NZ_CP089943:16915-17166 [Erwinia tracheiphila]
ATGCCAAACCTCATTCACAGCGATACAACAGCCAGCATCAGTGAGCTGAAGAAAAACCCTATGGCCACTGTCAATGCAGG
CGCCGGCTCTCCCGTGGCTATTCTGAACCATAACCAACCTGCTTTTTACTGTGTGCCAGCTGAACTCTATGAGCAGATGC
TCGAATACATTGACGAGGAAGAGCTTGCTAAACTGGTTACTAAACGCAGCAAACAGGCATTGCATGATGTGGATCTGGAT
AGCTACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References