187680

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 969445..970918 Replicon chromosome
Accession NZ_CP068734
Organism Mycoplasmopsis bovis strain J6 isolate J6

Toxin (Protein)


Gene name abiEi Uniprot ID -
Locus tag JNG56_RS04330 Protein ID WP_152028827.1
Coordinates 970052..970918 (+) Length 289 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID -
Locus tag JNG56_RS04325 Protein ID WP_152028826.1
Coordinates 969445..970059 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNG56_RS04295 965010..965669 + 660 WP_226088677.1 variable surface lipoprotein -
JNG56_RS04300 (JNG56_04240) 965690..965968 - 279 WP_226066048.1 hypothetical protein -
JNG56_RS04305 966266..967072 - 807 WP_226088678.1 variable surface lipoprotein -
JNG56_RS04310 (JNG56_04250) 967499..967684 - 186 Protein_829 variable surface lipoprotein -
JNG56_RS04315 (JNG56_04255) 968239..968424 - 186 Protein_830 variable surface lipoprotein -
JNG56_RS04320 (JNG56_04260) 968595..969263 - 669 WP_226088679.1 variable surface lipoprotein -
JNG56_RS04325 (JNG56_04265) 969445..970059 + 615 WP_152028826.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
JNG56_RS04330 (JNG56_04270) 970052..970918 + 867 WP_152028827.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
JNG56_RS04730 971032..971496 + 465 Protein_834 variable surface lipoprotein -
JNG56_RS04340 (JNG56_04285) 972095..972373 + 279 WP_226066048.1 hypothetical protein -
JNG56_RS04345 (JNG56_04290) 972408..972728 + 321 WP_226088680.1 hypothetical protein -
JNG56_RS04350 (JNG56_04295) 972919..973089 - 171 WP_226088681.1 variable surface lipoprotein -
JNG56_RS04355 (JNG56_04300) 973169..973387 - 219 WP_226088682.1 hypothetical protein -
JNG56_RS04360 (JNG56_04305) 973758..973892 - 135 Protein_839 variable surface lipoprotein -
JNG56_RS04365 (JNG56_04310) 974337..974543 - 207 WP_226088683.1 hypothetical protein -
JNG56_RS04735 974544..974591 - 48 WP_268919124.1 hypothetical protein -
JNG56_RS04370 (JNG56_04315) 975170..975355 + 186 WP_226088684.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-234)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-59)


Sequences

Toxin        


Download         Length: 289 a.a.        Molecular weight: 33522.63 Da        Isoelectric Point: 6.5024

>T187680 WP_152028827.1 NZ_CP068734:970052-970918 [Mycoplasmopsis bovis]
MNKNKLISLCHKIADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKAEELTNNDEI

Download         Length: 867 bp

>T187680 NZ_CP068734:970052-970918 [Mycoplasmopsis bovis]
ATGAATAAAAATAAATTAATAAGTTTGTGTCATAAAATTGCTGATGAAAATAACGCAAATTTCAATGTTGTTTTAATTCA
ATATTTTATGGAAAGCATTCTACGAAGAATATCTAAAAGCAATGAGAGAGACAATTTTGTGTTCAAGGGCGGTTTTCTTT
TATCTAACATTATGGGGTTAGATAAAAGAGCTACAATGGATATTGATTTGGAGCTAATAAAAACTCAAAAGATAAGTGCT
TCTAAAATATTAGAAAAATTTAAAAGTATATTAAACGCTGATGACATCGATGGAATTAGATATCACATTCTTAAGTATAC
TGACATTCGAAAGGAGCATAAATATAGTGGCATTAACATATCAGTCCTATGTCAAATAGAGAATATAAAACAAGTTATTT
CTATAGATATTGCATCGGGCGATGTCATTACACCTAAGGAAATTGTTTATGAATACAAAAGTATATTTTCAAATCAGGAT
TTTTCTATTTTAGCTTATAACATTGAAACTATGTTATCTGAAAAGCTTGAGACAATATTTTCTTTTGGTCACTTAAATAC
AAGATTTAAAGATTTTTATGATGTTTATGTTATATACACTTTTAAAAAGAAGGACATTGATATTAATAGGCTCAAGGATG
CTTGCTACAACACATTCAAAAATAGAAACAGCGAATTTAACATACAACAATTGTTGGAACTAATTACCAATATTGCTTTC
AATCCATTGATGAATGAAAGATGAAAAAAGTATATAAGTCAGATAGCAAATCAGCAGGAAATAGACTTTAAAGCCATTAC
TAATTCAATAATAGAACTACTAGAACTAATTAAGGCCGAGGAATTAACAAATAATGATGAAATTTAA

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 24085.79 Da        Isoelectric Point: 9.7565

>AT187680 WP_152028826.1 NZ_CP068734:969445-970059 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMIAKGVLIRKAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE

Download         Length: 615 bp

>AT187680 NZ_CP068734:969445-970059 [Mycoplasmopsis bovis]
ATGGAACAAAAAAACTTAAATTCAAAATATTACAATGCAATTTTTAAACTGTTGCATAAAAATAACGGTGTTATCACATA
TAAGCAACTAAAAGAAAACAATATATCTTCTATATATTTAACAAGAATGATAGCAAAAGGTGTTCTTATTAGAAAAGCTA
AAGGCATTTATATTCTTAGTGATGGACATTACGATGAATATTATTTCTTAAGCAAAAACTATAAATCGTTAATCTTTTCT
CATTATAGTGCACTATATTTAAATAATATTATTGACATTTTTCCGCATCAAATTGACGTTACAGTTTACAGTGGCTATAA
TGCAAAAGGCATTAAGAAGCATGCAAATGTTTACTACTGTGATAGGAATAAACATTCAATTGGACTATCTGAATCAAAAA
CATTATTTGGAAACAAAGTTAAGGTATATGACTTTGAGAGAACAATTTGTGATTTTGTAAAACTACGCAAGAAAACAGAT
AGCGAAATCTTTTCTAAGCTTATTAGTGCATATATTAAATATGAAAATAGAGATTGAAAAAAATTGTATGAATACGCCTA
TGAATTAGGCATACACAAAAAAATATCGGAGATATTTGAACTATTTTATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References