Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 1008626..1009137 Replicon chromosome
Accession NZ_CP068712
Organism Staphylococcus pseudoxylosus strain 14AME19

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag JMB28_RS04700 Protein ID WP_039069747.1
Coordinates 1008934..1009137 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag JMB28_RS04695 Protein ID WP_039069748.1
Coordinates 1008626..1008919 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMB28_RS04670 1003744..1004532 + 789 WP_069792681.1 hydroxyethylthiazole kinase -
JMB28_RS04675 1004535..1005173 + 639 WP_039069052.1 thiamine phosphate synthase -
JMB28_RS04680 1005261..1006130 + 870 WP_069792680.1 membrane protein insertase YidC -
JMB28_RS04685 1006248..1006853 - 606 WP_172643910.1 HD domain-containing protein -
JMB28_RS04690 1006999..1008483 - 1485 WP_069792679.1 cardiolipin synthase -
JMB28_RS04695 1008626..1008919 + 294 WP_039069748.1 copper-sensing transcriptional repressor CsoR Antitoxin
JMB28_RS04700 1008934..1009137 + 204 WP_039069747.1 hypothetical protein Toxin
JMB28_RS04705 1009358..1009498 + 141 WP_017722111.1 hypothetical protein -
JMB28_RS04710 1009932..1011137 - 1206 WP_039069746.1 rod shape-determining protein RodA -
JMB28_RS04715 1011389..1012459 + 1071 WP_039069745.1 D-alanine--D-alanine ligase -
JMB28_RS04720 1012472..1013827 + 1356 WP_069792678.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(14-92)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 7617.65 Da        Isoelectric Point: 4.1520

>T187664 WP_039069747.1 NZ_CP068712:1008934-1009137 [Staphylococcus pseudoxylosus]
VQSKVINISVINTEQQQYQIKQQLMNVIGVHNVAIDSDKGEILIDFETPASLNNLEKEIYDLGYQIL

Download         Length: 204 bp

>T187664 NZ_CP089940:c2120198-2119815 [Erwinia tracheiphila]
ATGAAATGGATTAGCGCTCAGGAGGTGATAGCGTTTCATGACCGTCTGCTTACAGCTTTGCCGGGCGTTCAGGGAATGCC
AGAGCCGGGAAGAGCAGAGGCGATCATTTATCGTGTTCAGAACCAGCTTTACTATGAAGGTGTTGAGGATATTCACGAAC
TGGCTGCAATGTATCTTGTCGCTATTTCGCGTGGTCATATCTTCAATGACGGCAATAAGCGAACCGCCTTTTTCGTTGCG
ATGGCTTTTTTAAAGCGCAATGGCATTGATATCCGTGACGAAGGTGATGAACTGGAAGAACTGACGGTATCCGCAGCGAT
GGGGGCAGTAAGCAGCGATGATATTGCTGCTGTTTTGCGCCGATTATCCATCAATCCCCACTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11223.90 Da        Isoelectric Point: 6.8626

>AT187664 WP_039069748.1 NZ_CP068712:1008626-1008919 [Staphylococcus pseudoxylosus]
VTEIQKAHHSEQIKSNLKSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATKLLDHHMKSCIMDKVEKGQQ
EEAMEELLVTFQKLMKD

Download         Length: 294 bp

>AT187664 NZ_CP089940:c2120416-2120195 [Erwinia tracheiphila]
ATGCGAACCTATACCACATCTCAGGCCCGGCAAAATATTGCCGAAGTAATGGAAGCGGCTACGGCTGGTGAGCCTGTAGA
AATAACTCGCCGCGATGGCTCTGCCGCTGTGCTTATCAGCCGAGATGATTTCAACGCGTGGCAGGAAGCAAAGCTGGATG
CTGAATTTGCCGAAATTATGGGGCGACACGGTCGTACCATTAAGGCGCTGGCCGACAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References