Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 234596..235122 Replicon plasmid p1
Accession NZ_CP068711
Organism Burkholderia thailandensis strain AW34-19p

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JMY07_RS30230 Protein ID WP_202821701.1
Coordinates 234596..234865 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JMY07_RS30235 Protein ID WP_202821702.1
Coordinates 234862..235122 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMY07_RS30205 229679..229945 - 267 WP_202821696.1 hypothetical protein -
JMY07_RS30210 229942..230748 - 807 WP_202821697.1 methyltransferase -
JMY07_RS30215 231429..231620 - 192 WP_202821698.1 hypothetical protein -
JMY07_RS30220 231622..231975 - 354 WP_202821699.1 hypothetical protein -
JMY07_RS30225 232682..234019 - 1338 WP_202821700.1 DUF3560 domain-containing protein -
JMY07_RS30230 234596..234865 - 270 WP_202821701.1 Txe/YoeB family addiction module toxin Toxin
JMY07_RS30235 234862..235122 - 261 WP_202821702.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JMY07_RS30240 235234..235839 - 606 WP_202821703.1 hypothetical protein -
JMY07_RS30245 235853..236377 - 525 WP_202821704.1 hypothetical protein -
JMY07_RS30250 236374..236577 - 204 WP_202821705.1 hypothetical protein -
JMY07_RS30255 237124..237963 - 840 WP_202821923.1 hypothetical protein -
JMY07_RS30260 238633..239769 - 1137 WP_202821706.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..303664 303664


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10655.03 Da        Isoelectric Point: 8.8834

>T187663 WP_202821701.1 NZ_CP068711:c234865-234596 [Burkholderia thailandensis]
MSVRRVLFTPDAWDDYVYWQGQDRKTLKRINQLIREAQRTPFEGIGKPEPLKANLSGFWSRRIDDTNRLVYEADDFQISI
ISCRYHYQA

Download         Length: 270 bp

>T187663 NZ_CP089940:c1557814-1557596 [Erwinia tracheiphila]
ATGACAAACAAAGTTCTTACTAAAACTGATTATCTTATGCGTTTAAGAAAGTGTCGTTCTATCGACACCCTGGAACGCGT
TATAGAAAAGAACAAATACGAATTATCCGACAATGAGCTGGCAGTATTTTATTCTGCTGCTGACCATCGCCTGGCTGAAC
TCACTATGAATAAGCTTTACGATAAGGTGCCTGTTTCAGTCTGGAAATTCATACGTTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9750.06 Da        Isoelectric Point: 6.7254

>AT187663 WP_202821702.1 NZ_CP068711:c235122-234862 [Burkholderia thailandensis]
MRTIHFSDARGNLKTVIDQVVDDADVTLITRRDAPNAVIMSQDYYDSLMETVHLLRSPANVAHLERSIAQLRKGKAKERK
LAEDTE

Download         Length: 261 bp

>AT187663 NZ_CP089940:c1558219-1557839 [Erwinia tracheiphila]
ATGGACGAGTATTCACCAAAAAGGCATGATATTGCACAATTAAAATTCTTGTGTGAAAATTTGTACGATGAAAGCATGAC
AACAATAGGTGACAGCCATCATGGATGGATTAACGATCCGACTTCTGCCAGCAATTTACAGCTTAACGATTTGATTGAGC
ACATAGCCTCATTTACCATGAATTACAAAATTAAACATATTGAAGATAGCGATCTGATTAGTCAGATTGATGAATATCTT
GATGACACTTTTATGCTCTTTAGTAATTACGGCATTAATGTTCAGGAACTGCAACGCTGGCGAAAATCAGCTGAAGGGTT
GTTTAGCATTTTTGCAGAGGAGTGCGCTCAAGTTGCCAATCCTGCGAGCCACTCGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References