Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 2567954..2569710 | Replicon | chromosome |
Accession | NZ_CP068710 | ||
Organism | Burkholderia thailandensis strain AW34-19p |
Toxin (Protein)
Gene name | doc | Uniprot ID | Q2T555 |
Locus tag | JMY07_RS27810 | Protein ID | WP_009900384.1 |
Coordinates | 2568805..2569710 (-) | Length | 302 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | Q2T556 |
Locus tag | JMY07_RS27805 | Protein ID | WP_009897321.1 |
Coordinates | 2567954..2568808 (-) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JMY07_RS27785 | 2563174..2564664 | - | 1491 | WP_009897313.1 | aldehyde dehydrogenase | - |
JMY07_RS27790 | 2564686..2565501 | - | 816 | WP_009897315.1 | aspartate dehydrogenase | - |
JMY07_RS27795 | 2565494..2567167 | - | 1674 | WP_009897317.1 | thiamine pyrophosphate-binding protein | - |
JMY07_RS27800 | 2567160..2567957 | - | 798 | WP_009897318.1 | SDR family oxidoreductase | - |
JMY07_RS27805 | 2567954..2568808 | - | 855 | WP_009897321.1 | IclR family transcriptional regulator | Antitoxin |
JMY07_RS27810 | 2568805..2569710 | - | 906 | WP_009900384.1 | alpha/beta fold hydrolase | Toxin |
JMY07_RS27815 | 2569727..2570254 | - | 528 | WP_009897327.1 | cupin domain-containing protein | - |
JMY07_RS27820 | 2570293..2571063 | - | 771 | WP_009897331.1 | SDR family oxidoreductase | - |
JMY07_RS27825 | 2571060..2572127 | - | 1068 | WP_009897333.1 | aromatic ring-hydroxylating dioxygenase subunit alpha | - |
JMY07_RS27830 | 2572162..2572473 | - | 312 | WP_009897334.1 | hypothetical protein | - |
JMY07_RS27835 | 2572475..2572792 | - | 318 | WP_009897336.1 | non-heme iron oxygenase ferredoxin subunit | - |
JMY07_RS27840 | 2573227..2574315 | + | 1089 | WP_009897338.1 | porin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 302 a.a. Molecular weight: 30752.67 Da Isoelectric Point: 8.4768
>T187662 WP_009900384.1 NZ_CP068710:c2569710-2568805 [Burkholderia thailandensis]
MSAISTTTTDASATPFAALLERFAERRAAAGGARTIGYREAGAAYAAHAGRDPVVLLHGIGSGAASWVRQLDALGATRRA
LAWDAPGYGVSSRVAADSPVASDYAASLAAWLDALRIERCVLVGHSLGAIVAGAFARQAGERLSGLLLISPAGGYGGAPA
DVRAERRDSRLALLASLGPQGLAAERSANMLSAQASDAARAWVRWNMARIVPAGYAQATHLLANADLASDLAHYRGRVAV
AVGADDTITPPAACERIARAAGAGLQVIPRAGHAGYVEAPDAYNALIDAFCRQCDGSRGAA
MSAISTTTTDASATPFAALLERFAERRAAAGGARTIGYREAGAAYAAHAGRDPVVLLHGIGSGAASWVRQLDALGATRRA
LAWDAPGYGVSSRVAADSPVASDYAASLAAWLDALRIERCVLVGHSLGAIVAGAFARQAGERLSGLLLISPAGGYGGAPA
DVRAERRDSRLALLASLGPQGLAAERSANMLSAQASDAARAWVRWNMARIVPAGYAQATHLLANADLASDLAHYRGRVAV
AVGADDTITPPAACERIARAAGAGLQVIPRAGHAGYVEAPDAYNALIDAFCRQCDGSRGAA
Download Length: 906 bp
>T187662 NZ_CP089940:c1347099-1346824 [Erwinia tracheiphila]
GTGCAATGGGTTAAATGGAAGGAATCAGCGCTCAACGATTTAGCCGACATTATTGATTATATTGAACAATATAACCCTGT
TGCGAGTCGAAAATTACATCAACAGATAGTACATGTAGCCGAAAACCTCCCTCAGCATCCTTATCTTTATCGTCCTGGCA
GAGTTGCTGGCACTCGCGAAATCGTTGTCCATCCGAACTATTTAGTTGTCTACCACATTGATGATTTTGAAATAGAAATT
CTGCGGGTATTGCATGCTCGCCAGGAATATCCGTAA
GTGCAATGGGTTAAATGGAAGGAATCAGCGCTCAACGATTTAGCCGACATTATTGATTATATTGAACAATATAACCCTGT
TGCGAGTCGAAAATTACATCAACAGATAGTACATGTAGCCGAAAACCTCCCTCAGCATCCTTATCTTTATCGTCCTGGCA
GAGTTGCTGGCACTCGCGAAATCGTTGTCCATCCGAACTATTTAGTTGTCTACCACATTGATGATTTTGAAATAGAAATT
CTGCGGGTATTGCATGCTCGCCAGGAATATCCGTAA
Antitoxin
Download Length: 285 a.a. Molecular weight: 31148.57 Da Isoelectric Point: 6.9978
>AT187662 WP_009897321.1 NZ_CP068710:c2568808-2567954 [Burkholderia thailandensis]
MSEPLLKDADDARNDSNYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYRL
GVAVLRLGFEYLSSLELTDLGLPVIEGLRDATGFTAHIVIRDGRDVVFVAKAQNAGHAFGSVRVNVGTRLPAHATTHGHV
LMGDLTLAELRTLYPERALERVTKATPETVDALFDVIRADARRGYGIGNSAFERDISVVTAPVRNEASRIVAVVTVTVPR
PEIDASLVADGLIDKVVRAAAELSRRLNYRSDDENTYLKALGLR
MSEPLLKDADDARNDSNYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYRL
GVAVLRLGFEYLSSLELTDLGLPVIEGLRDATGFTAHIVIRDGRDVVFVAKAQNAGHAFGSVRVNVGTRLPAHATTHGHV
LMGDLTLAELRTLYPERALERVTKATPETVDALFDVIRADARRGYGIGNSAFERDISVVTAPVRNEASRIVAVVTVTVPR
PEIDASLVADGLIDKVVRAAAELSRRLNYRSDDENTYLKALGLR
Download Length: 855 bp
>AT187662 NZ_CP089940:c1347286-1347086 [Erwinia tracheiphila]
ATGACCACTAAACTGTCCCCCATCGTGTCTGAATTTGAGACTCAGGAGCAGGCTGACAGCTATGATCGCTGGTTCCGGGC
TAAGGTTCAGGTCGCGCTGGACGACCCACGTCCGGGTATTCCTCACGATGATGCAATGGCAAAGCTGGAAGCAATGCTGG
AAGAGAGACGGACCTTGAGGGCAAAGCGTGCAATGGGTTAA
ATGACCACTAAACTGTCCCCCATCGTGTCTGAATTTGAGACTCAGGAGCAGGCTGACAGCTATGATCGCTGGTTCCGGGC
TAAGGTTCAGGTCGCGCTGGACGACCCACGTCCGGGTATTCCTCACGATGATGCAATGGCAAAGCTGGAAGCAATGCTGG
AAGAGAGACGGACCTTGAGGGCAAAGCGTGCAATGGGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|