Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070921..2071066 Replicon chromosome
Accession NZ_CP068689
Organism Klebsiella pneumoniae subsp. pneumoniae strain RJBSI76

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070957..2071059 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070921..2071066 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5002_RS10120 2066051..2068111 + 2061 WP_004151449.1 oligopeptidase B -
I5002_RS10125 2068115..2068774 - 660 WP_002911407.1 exodeoxyribonuclease X -
I5002_RS10130 2068853..2069083 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I5002_RS10135 2069196..2069570 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I5002_RS10140 2069574..2070443 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
I5002_RS10145 2070460..2070798 + 339 WP_002911404.1 YebY family protein -
- 2070921..2071066 - 146 - - Antitoxin
- 2070957..2071059 + 103 - - Toxin
I5002_RS10150 2071434..2071577 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I5002_RS10155 2071682..2072650 - 969 WP_004151446.1 VirK/YbjX family protein -
I5002_RS10160 2072807..2073460 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
I5002_RS10165 2073457..2073648 - 192 WP_002911395.1 YebW family protein -
I5002_RS10170 2073746..2073985 - 240 WP_002911393.1 YebV family protein -
I5002_RS10175 2074101..2075534 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T187568 NZ_CP068689:2070957-2071059 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT187568 NZ_CP068689:c2071066-2070921 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References