Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1898945..1899504 Replicon chromosome
Accession NZ_CP068647
Organism Vibrio parahaemolyticus strain TJ-187

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JHS88_RS08640 Protein ID WP_031846599.1
Coordinates 1899226..1899504 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JHS88_RS08635 Protein ID WP_031846598.1
Coordinates 1898945..1899229 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JHS88_RS08595 (JHS88_08585) 1894050..1894130 - 81 WP_078532227.1 DUF3265 domain-containing protein -
JHS88_RS08600 (JHS88_08590) 1894145..1894567 - 423 WP_140392184.1 hypothetical protein -
JHS88_RS08605 (JHS88_08595) 1894715..1895599 - 885 WP_031778322.1 hypothetical protein -
JHS88_RS08610 (JHS88_08605) 1896600..1896767 - 168 WP_162457647.1 DUF3265 domain-containing protein -
JHS88_RS08615 (JHS88_08610) 1897040..1897132 - 93 WP_079386106.1 DUF3265 domain-containing protein -
JHS88_RS08620 (JHS88_08615) 1897147..1897704 - 558 WP_029857376.1 hypothetical protein -
JHS88_RS08625 (JHS88_08620) 1897731..1897823 - 93 WP_072612521.1 DUF3265 domain-containing protein -
JHS88_RS08630 1898291..1898403 - 113 Protein_1670 DUF3265 domain-containing protein -
JHS88_RS08635 (JHS88_08630) 1898945..1899229 + 285 WP_031846598.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JHS88_RS08640 (JHS88_08635) 1899226..1899504 + 279 WP_031846599.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
JHS88_RS08645 (JHS88_08640) 1899533..1899625 - 93 WP_079766442.1 DUF3265 domain-containing protein -
JHS88_RS08650 (JHS88_08645) 1899640..1899993 - 354 WP_031829440.1 hypothetical protein -
JHS88_RS08655 (JHS88_08650) 1900166..1900921 - 756 WP_006741457.1 DUF3944 domain-containing protein -
JHS88_RS08660 (JHS88_08655) 1901143..1902762 - 1620 WP_228846245.1 DUF4263 domain-containing protein -
JHS88_RS08665 (JHS88_08660) 1902928..1903194 - 267 WP_025527397.1 barstar family protein -
JHS88_RS08670 (JHS88_08665) 1903397..1903903 + 507 WP_062905969.1 hypothetical protein -
JHS88_RS08675 (JHS88_08670) 1904055..1904273 - 219 WP_031778385.1 DUF6500 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1884933..1917100 32167


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-45)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10935.69 Da        Isoelectric Point: 4.3324

>T187476 WP_031846599.1 NZ_CP068647:1899226-1899504 [Vibrio parahaemolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPDISMIVSYWIEGDIIRIM
RVLHQKQKFPMD

Download         Length: 279 bp

>T187476 NZ_CP089870:720871-721356 [Klebsiella pneumoniae]
ATGATCTTGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGACCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTAGTTAAT
GCCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11055.37 Da        Isoelectric Point: 9.2167

>AT187476 WP_031846598.1 NZ_CP068647:1898945-1899229 [Vibrio parahaemolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVDHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT187476 NZ_CP089870:720581-720874 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References