Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910493..1910638 Replicon chromosome
Accession NZ_CP068618
Organism Klebsiella pneumoniae strain 41968

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910529..1910631 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910493..1910638 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMZ79_RS09320 1905623..1907683 + 2061 WP_032422099.1 oligopeptidase B -
JMZ79_RS09325 1907687..1908346 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMZ79_RS09330 1908425..1908655 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMZ79_RS09335 1908768..1909142 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMZ79_RS09340 1909146..1910015 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
JMZ79_RS09345 1910032..1910370 + 339 WP_002911404.1 YebY family protein -
- 1910493..1910638 - 146 - - Antitoxin
- 1910529..1910631 + 103 - - Toxin
JMZ79_RS09350 1911006..1911149 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMZ79_RS09355 1911254..1912222 - 969 WP_004151446.1 VirK/YbjX family protein -
JMZ79_RS09360 1912379..1913032 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
JMZ79_RS09365 1913029..1913220 - 192 WP_002911395.1 YebW family protein -
JMZ79_RS09370 1913318..1913557 - 240 WP_002911393.1 YebV family protein -
JMZ79_RS09375 1913673..1915106 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T187432 NZ_CP068618:1910529-1910631 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT187432 NZ_CP068618:c1910638-1910493 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References