Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2014951..2015096 | Replicon | chromosome |
| Accession | NZ_CP068614 | ||
| Organism | Klebsiella pneumoniae strain 42362 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2014987..2015089 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2014951..2015096 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMZ78_RS09870 | 2010081..2012141 | + | 2061 | WP_032422099.1 | oligopeptidase B | - |
| JMZ78_RS09875 | 2012145..2012804 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMZ78_RS09880 | 2012883..2013113 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMZ78_RS09885 | 2013226..2013600 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMZ78_RS09890 | 2013604..2014473 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| JMZ78_RS09895 | 2014490..2014828 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2014951..2015096 | - | 146 | - | - | Antitoxin |
| - | 2014987..2015089 | + | 103 | - | - | Toxin |
| JMZ78_RS09900 | 2015464..2015607 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMZ78_RS09905 | 2015712..2016680 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| JMZ78_RS09910 | 2016837..2017490 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| JMZ78_RS09915 | 2017487..2017678 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMZ78_RS09920 | 2017776..2018015 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMZ78_RS09925 | 2018131..2019564 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T187412 NZ_CP068614:2014987-2015089 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT187412 NZ_CP068614:c2015096-2014951 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT