Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1950035..1950180 Replicon chromosome
Accession NZ_CP068610
Organism Klebsiella pneumoniae strain 45706

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1950071..1950173 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1950035..1950180 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMZ75_RS09595 1945165..1947225 + 2061 WP_004151449.1 oligopeptidase B -
JMZ75_RS09600 1947229..1947888 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMZ75_RS09605 1947967..1948197 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMZ75_RS09610 1948310..1948684 + 375 WP_023286640.1 CopC domain-containing protein YobA -
JMZ75_RS09615 1948688..1949557 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
JMZ75_RS09620 1949574..1949912 + 339 WP_016529031.1 YebY family protein -
- 1950035..1950180 - 146 - - Antitoxin
- 1950071..1950173 + 103 - - Toxin
JMZ75_RS09625 1950547..1950690 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMZ75_RS09630 1950795..1951763 - 969 WP_074194451.1 VirK/YbjX family protein -
JMZ75_RS09635 1951920..1952573 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
JMZ75_RS09640 1952570..1952761 - 192 WP_002911395.1 YebW family protein -
JMZ75_RS09645 1952859..1953098 - 240 WP_002911393.1 YebV family protein -
JMZ75_RS09650 1953214..1954647 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T187393 NZ_CP068610:1950071-1950173 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT187393 NZ_CP068610:c1950180-1950035 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References