Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974731..1974876 Replicon chromosome
Accession NZ_CP068602
Organism Klebsiella pneumoniae strain 59493

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974767..1974869 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974731..1974876 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMZ77_RS09560 1969861..1971921 + 2061 WP_032422099.1 oligopeptidase B -
JMZ77_RS09565 1971925..1972584 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMZ77_RS09570 1972663..1972893 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMZ77_RS09575 1973006..1973380 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMZ77_RS09580 1973384..1974253 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
JMZ77_RS09585 1974270..1974608 + 339 WP_002911404.1 YebY family protein -
- 1974731..1974876 - 146 - - Antitoxin
- 1974767..1974869 + 103 - - Toxin
JMZ77_RS09590 1975244..1975387 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMZ77_RS09595 1975492..1976460 - 969 WP_004151446.1 VirK/YbjX family protein -
JMZ77_RS09600 1976617..1977270 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
JMZ77_RS09605 1977267..1977458 - 192 WP_002911395.1 YebW family protein -
JMZ77_RS09610 1977556..1977795 - 240 WP_002911393.1 YebV family protein -
JMZ77_RS09615 1977911..1979344 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T187372 NZ_CP068602:1974767-1974869 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT187372 NZ_CP068602:c1974876-1974731 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References