Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3205548..3205693 Replicon chromosome
Accession NZ_CP068572
Organism Klebsiella pneumoniae strain IR1251

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3205555..3205657 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3205548..3205693 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJV77_RS15845 3201080..3202513 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JJV77_RS15850 3202629..3202868 + 240 WP_002911393.1 YebV family protein -
JJV77_RS15855 3202966..3203157 + 192 WP_002911395.1 YebW family protein -
JJV77_RS15860 3203154..3203807 - 654 WP_016529030.1 protein-serine/threonine phosphatase -
JJV77_RS15865 3203964..3204932 + 969 WP_004151446.1 VirK/YbjX family protein -
JJV77_RS15870 3205037..3205180 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3205548..3205693 + 146 - - Antitoxin
- 3205555..3205657 - 103 - - Toxin
JJV77_RS15875 3205816..3206154 - 339 WP_016529031.1 YebY family protein -
JJV77_RS15880 3206171..3207040 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JJV77_RS15885 3207044..3207418 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JJV77_RS15890 3207531..3207761 + 231 WP_040147502.1 DNA polymerase III subunit theta -
JJV77_RS15895 3207840..3208499 + 660 WP_002911407.1 exodeoxyribonuclease X -
JJV77_RS15900 3208503..3210563 - 2061 WP_206925937.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T187308 NZ_CP068572:c3205657-3205555 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT187308 NZ_CP068572:3205548-3205693 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References