Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /RES-TIGR02293 |
Location | 241397..242307 | Replicon | plasmid unnamed3 |
Accession | NZ_CP068443 | ||
Organism | Pantoea agglomerans strain ZJU23 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | JK642_RS21970 | Protein ID | WP_069026891.1 |
Coordinates | 241837..242307 (+) | Length | 157 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | JK642_RS21965 | Protein ID | WP_064703869.1 |
Coordinates | 241397..241840 (+) | Length | 148 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JK642_RS21935 (JK642_21870) | 236466..237314 | - | 849 | WP_189327956.1 | transporter substrate-binding domain-containing protein | - |
JK642_RS21940 (JK642_21875) | 237336..238523 | - | 1188 | WP_235765477.1 | M20 family metallopeptidase | - |
JK642_RS21945 (JK642_21880) | 238765..239664 | - | 900 | WP_235765478.1 | alpha/beta hydrolase | - |
JK642_RS21950 (JK642_21885) | 239715..240329 | - | 615 | WP_235765479.1 | TetR/AcrR family transcriptional regulator | - |
JK642_RS21955 (JK642_21890) | 240543..240960 | + | 418 | Protein_232 | LysR substrate-binding domain-containing protein | - |
JK642_RS21960 (JK642_21895) | 240995..241252 | - | 258 | Protein_233 | aldo/keto reductase | - |
JK642_RS21965 (JK642_21900) | 241397..241840 | + | 444 | WP_064703869.1 | DUF2384 domain-containing protein | Antitoxin |
JK642_RS21970 (JK642_21905) | 241837..242307 | + | 471 | WP_069026891.1 | RES family NAD+ phosphorylase | Toxin |
JK642_RS21975 (JK642_21910) | 242479..243510 | + | 1032 | WP_010670602.1 | AI-2E family transporter | - |
JK642_RS21980 (JK642_21915) | 243499..246228 | - | 2730 | WP_182687108.1 | cation-transporting P-type ATPase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | iroN | 1..567588 | 567588 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 17466.90 Da Isoelectric Point: 4.7699
>T187236 WP_069026891.1 NZ_CP068443:241837-242307 [Pantoea agglomerans]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK
Download Length: 471 bp
>T187236 NZ_CP089780:c753978-753670 [Mycobacterium tuberculosis]
ATGCGGCGCGGTGAATTGTGGTTTGCCGCCACACCTGGTGGTGACAGACCAGTACTTGTCCTTACCAGAGATCCGGTGGC
AGACCGCATCGGCGCGGTCGTTGTGGTGGCCCTAACCCGCACCCGCCGAGGCCTGGTGTCGGAATTGGAGCTCACGGCCG
TCGAAAACCGTGTTCCGAGCGACTGCGTCGTCAACTTCGACAACATTCATACGTTGCCACGCACCGCATTCCGACGCCGC
ATCACCCGGCTGTCCCCGGCCCGCCTGCACGAAGCCTGTCAAACACTCCGGGCGAGCACGGGGTGTTGA
ATGCGGCGCGGTGAATTGTGGTTTGCCGCCACACCTGGTGGTGACAGACCAGTACTTGTCCTTACCAGAGATCCGGTGGC
AGACCGCATCGGCGCGGTCGTTGTGGTGGCCCTAACCCGCACCCGCCGAGGCCTGGTGTCGGAATTGGAGCTCACGGCCG
TCGAAAACCGTGTTCCGAGCGACTGCGTCGTCAACTTCGACAACATTCATACGTTGCCACGCACCGCATTCCGACGCCGC
ATCACCCGGCTGTCCCCGGCCCGCCTGCACGAAGCCTGTCAAACACTCCGGGCGAGCACGGGGTGTTGA
Antitoxin
Download Length: 148 a.a. Molecular weight: 16463.84 Da Isoelectric Point: 9.9250
>AT187236 WP_064703869.1 NZ_CP068443:241397-241840 [Pantoea agglomerans]
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS
Download Length: 444 bp
>AT187236 NZ_CP089780:c754210-753965 [Mycobacterium tuberculosis]
ATGCTCAGCTTCCGCGCCGACGACCACGACGTCGACCTGGCCGACGCGTGGGCGCGTCGCCTACACATCGGCCGCTCCGA
GCTGCTGCGCGATGCGCTGCGACGTCACTTGGCCGCGCTGGCCGCGGACCAGGATGTCCAGGCCTACACCGAGCGACCGT
TGACGGACGACGAGAACGCACTGGCTGAGATCGCCGACTGGGGGCCGGCGGAGGACTGGGCCGACTGGGCCGATGCGGCG
CGGTGA
ATGCTCAGCTTCCGCGCCGACGACCACGACGTCGACCTGGCCGACGCGTGGGCGCGTCGCCTACACATCGGCCGCTCCGA
GCTGCTGCGCGATGCGCTGCGACGTCACTTGGCCGCGCTGGCCGCGGACCAGGATGTCCAGGCCTACACCGAGCGACCGT
TGACGGACGACGAGAACGCACTGGCTGAGATCGCCGACTGGGGGCCGGCGGAGGACTGGGCCGACTGGGCCGATGCGGCG
CGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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