Detailed information of TA system TA187226

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1414496..1415141
• Replicon: chromosome
• Accession: NZ_CP068437
• Organism: Shewanella sp. KX20019

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: JK628_RS06190
• Protein ID: WP_202288545.1
• Coordinates: 1414716..1415141 (+)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: JK628_RS06185
• Protein ID: WP_202289731.1
• Coordinates: 1414496..1414735 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JK628_RS06160	1409810..1410610	+	801	WP_202288537.1	sulfite exporter TauE/SafE family protein	-
JK628_RS06165	1410693..1411544	+	852	WP_202288538.1	thymidylate synthase	-
JK628_RS06170	1411868..1413043	+	1176	WP_202288539.1	Na+/H+ antiporter NhaA	-
JK628_RS06175	1413040..1413423	+	384	WP_202288541.1	hypothetical protein	-
JK628_RS06180	1413485..1414393	+	909	WP_202288543.1	transcriptional activator NhaR	-
JK628_RS06185	1414496..1414735	+	240	WP_202289731.1	succinate dehydrogenase assembly factor 2	Antitoxin
JK628_RS06190	1414716..1415141	+	426	WP_202288545.1	hypothetical protein	Toxin
JK628_RS06195	1415158..1416768	-	1611	WP_202288547.1	L-aspartate oxidase	-
JK628_RS06200	1417218..1417796	+	579	WP_202288549.1	RNA polymerase sigma factor RpoE	-
JK628_RS06205	1417822..1418418	+	597	WP_202288551.1	anti-sigma factor	-
JK628_RS06210	1418431..1419363	+	933	WP_202288553.1	MucB/RseB C-terminal domain-containing protein	-
JK628_RS06215	1419376..1419840	+	465	WP_202288555.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-135)

Antitoxin

• Flavinator of succinate dehydrogenase (4-74)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 16607.36 Da
• Isoelectric Point: 8.6460

>T187226 WP_202288545.1 NZ_CP068437:1414716-1415141 [Shewanella sp. KX20019]
VVAQQHSFHLSSSFDQRFSLVVVASLCFISFMVWPYGESFSYLFCKSLIFILSISYFSWQFWQLKHWSCQFILSAEGNGR
LNQKQGFVIKGKPMITPFALMFDIQCETEVKRLVVWADMLDDTSYRHLCRLLLQSNQRRLN

Nucleotide

• Length: 426 bp

>T187226 NZ_CP089780:c443192-442599 [Mycobacterium tuberculosis]
GTGAAGCGGCTCGATCTGGTCGCCGGGCCCAACGGCGCCGGCAAGTCGACGTTCGTCGCCCTCACGCTGGCGCCCTTGCT
GCCCGGCATCGTCTTCGTCAACGCCGACGAAATCGCCAAACAACGCTGGCCCGACGACCCAACATCGCACGCCTACCAGG
CGGCGCAGGTCGCCGCCGACACCCGCGCGAGGCTCATCGACTTGGGCCGGCCGTTCATTGCCGAGACGGTGTTCTCGCAC
CCATCGAAGCTCGAGCTCATCCGCACCGCGCGCACGGCCGGCTACACCGTCGTACTGCACGTGTTGGTTATCCCCGAAGG
CCTGGCGGTCGAGCGCGTCAGGCATCGCGTCGCCGCGGGCGGCCACGATGTGCCGGAGACCAAGATCCGCGAGCGTCACC
GCCGGCTGGCCGAGCTTGTCGCCCAGGCCATCACGCTGGCCGACGGCGCCACCGTCTATGACAACAGCCGGCTCGCGGGC
CCGCGGATCGTCGCTCAGTTCAGCGGGGGTGGCATCATCGGGCGCGCATGCTGGCCTTCGTGGACGCCGCCACCCTTGAT
GTCACGCTGGAGTAACAGGCCTGAGACGGCGTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9313.89 Da
• Isoelectric Point: 5.6987

>AT187226 WP_202289731.1 NZ_CP068437:1414496-1414735 [Shewanella sp. KX20019]
MKIARVRWACRRGMLELDVLFQPFVELHYEAMSNADKNIFVRLLESEDPELFAWFMGHEVCKDPEFAEMIVRVRGRPAA

Nucleotide

• Length: 240 bp

>AT187226 NZ_CP089780:c443610-443221 [Mycobacterium tuberculosis]
GTGCCCAAAGCCGTCGACCGCGTCACGCGCGTCGCCGCGGATCTGGTGGACAGCGCGGCGGCCGAGGGTGCTCGTCAGAG
CCGTTCGGCCAAGCAGCAGCTCGACCACTGGGCCCGCGTCGGTCGGGCGGTGTCGAACCAGCACACGGCGTCGCGGCGCC
GCGTGGAAGCTGCGCTCGCGGGGCATCTGCCGATGACGGACCTGACGCTGGAGGAGGGCGTGGTGTTCAACGCCGAGATC
TCCGCAGCTATCGAGGAGCGCCTGTCGCGAACCAACTACGGCGACGTGCTCGCCGCGCAGGGCATCACCACGGTCGCCCT
GAACGACGCGGGCGACATCGTCGAGCACCGGCCAGACGGCACCTCGGTCGTGCTGGCGGCCACGCCGTGA