Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 121682..122237 Replicon chromosome
Accession NZ_CP068346
Organism Succinivibrio dextrinosolvens strain ASCUSBF53

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JKJ12_RS12200 Protein ID WP_202109149.1
Coordinates 121953..122237 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JKJ12_RS12195 Protein ID WP_202109258.1
Coordinates 121682..121960 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKJ12_RS12165 117184..117396 - 213 WP_074942268.1 hypothetical protein -
JKJ12_RS12170 117655..118248 - 594 WP_202109145.1 hypothetical protein -
JKJ12_RS12175 118508..119848 + 1341 WP_202109146.1 FAD-binding oxidoreductase -
JKJ12_RS12180 119897..120322 - 426 WP_074942264.1 cold shock domain-containing protein -
JKJ12_RS12185 120397..120696 - 300 WP_202109147.1 hypothetical protein -
JKJ12_RS12190 120875..121612 + 738 WP_202109148.1 SDR family NAD(P)-dependent oxidoreductase -
JKJ12_RS12195 121682..121960 + 279 WP_202109258.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JKJ12_RS12200 121953..122237 + 285 WP_202109149.1 type II toxin-antitoxin system YafQ family toxin Toxin
JKJ12_RS12205 122350..122610 + 261 WP_143098536.1 hypothetical protein -
JKJ12_RS12210 122620..122877 + 258 WP_202109150.1 hypothetical protein -
JKJ12_RS12215 122917..123945 - 1029 WP_202109151.1 hypothetical protein -
JKJ12_RS12220 124146..124547 + 402 WP_074942257.1 hypothetical protein -
JKJ12_RS12225 124574..125959 - 1386 WP_202109152.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 92086..148172 56086


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(10-89)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11154.81 Da        Isoelectric Point: 9.0090

>T187152 WP_202109149.1 NZ_CP068346:121953-122237 [Succinivibrio dextrinosolvens]
MTRQVIWTKQFKKDYKLAIKRNQNIELLDDIIRKIAQNIPLPQSNKDHALNGNWKGFRECHIQPDWLLIYQISDDLLVLS
LTRTGTHSDLFNHE

Download         Length: 285 bp

>T187152 NZ_CP089778:c3081135-3080740 [Mycobacterium tuberculosis]
GTGATCGTCGATACGTCGGCCATCGTCGCCATCGTGAGCGGGGAATCGGGCGCGCAGGTGCTCAAGGAGGCGCTGGAGCG
GTCACCGAACTCCCGAATGTCCGCGCCCAACTACGTCGAACTGTGCGCGATCATGCAGCGGCGGGACCGGCCGGAGATCT
CTCGATTGGTGGACCGTTTGCTGGACGACTACGGAATCCAGGTCGAAGCCGTCGACGCCGACCAAGCCCGCGTGGCCGCG
CAGGCGTATCGCGACTACGGCCGCGGCAGCGGCCATCCGGCCCGTCTCAACCTCGGCGACACCTACAGCTACGCCCTGGC
CCAGGTCACCGGGGAGCCGCTGCTGTTTCGTGGCGATGACTTCACGCATACCGATATCCGGCCCGCGTGCACCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10332.88 Da        Isoelectric Point: 5.0955

>AT187152 WP_202109258.1 NZ_CP068346:121682-121960 [Succinivibrio dextrinosolvens]
IMANTINYTCRIDSEVKQKGEVLFKELGMSLSTAINVFLKEAIRTGGFPFNVCLKNPNKETLTAMMESNQLLNDPNTKTY
SVEDALKELKND

Download         Length: 279 bp

>AT187152 NZ_CP089778:c3080714-3080448 [Mycobacterium tuberculosis]
ATGCATCGCGGATATGCATTAGTAGTATGCTCTCCGGGTGTGACGCGCACCATGATCGACATCGATGACGACCTGCTCGC
TCGGGCCGCCAAGGAACTGGGTACCACGACAAAGAAAGACACCGTGCATGCCGCGCTGCGGGCCGCGTTGCGAGCCAGTG
CCGCGCGCTCGCTCATGAACCGGATGGCCGAGAACGCCACCGGAACCCAGGACGAAGCTCTGGTCAACGCAATGTGGCGA
GACGGCCACCCAGAGAACACGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References