Detailed information of TA system TA187150

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 1363564..1364110
• Replicon: chromosome
• Accession: NZ_CP068345
• Organism: Succinivibrio dextrinosolvens strain ASCUSBF53

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JKJ12_RS05785
• Protein ID: WP_202107596.1
• Coordinates: 1363564..1363836 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JKJ12_RS05790
• Protein ID: WP_202107597.1
• Coordinates: 1363829..1364110 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JKJ12_RS05775	1360990..1362411	+	1422	WP_202107594.1	YcjX family protein	-
JKJ12_RS05780	1362408..1363502	+	1095	WP_202107595.1	TIGR01620 family protein	-
JKJ12_RS05785	1363564..1363836	-	273	WP_202107596.1	type II toxin-antitoxin system YafQ family toxin	Toxin
JKJ12_RS05790	1363829..1364110	-	282	WP_202107597.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
JKJ12_RS05795	1364207..1366312	-	2106	WP_202107598.1	transglycosylase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (1-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (3-75)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10677.55 Da
• Isoelectric Point: 10.2198

>T187150 WP_202107596.1 NZ_CP068345:c1363836-1363564 [Succinivibrio dextrinosolvens]
MLKIIPTRQFKKDLKLLKNNNNDLQTLKNVISVLQKEHSLHGLFNDHALRGNYKDYRECHIKPDLLLIYRIENDKLILIL
KRVGSHSELF

Nucleotide

• Length: 273 bp

>T187150 NZ_CP089778:c2986724-2986401 [Mycobacterium tuberculosis]
TTGACCCACAAGCGCACTAAACGCCAGCCAGCCATCGCCGCAGGGCTCAACGCCCCGCGTCGGAATCGCGTTGGGCGGCA
ACATGGTTGGCCGGCCGACGTTCCGTCCGCCGAGCAGCGCCGCGCCCAACGGCAGCGCGACCTCGAGGCTATCCGCCGAG
CGTACGCCGAGATGGTGGCGACATCACACGAAATCGACGACGACACAGCCGAACTGGCGCTGTTGTCGATGCATCTCGAC
GATGAGCAGCGCCGGCTTGAGGCGGGGATGAAGCTCGGCTGGCATCCGTATCACTTCCCCGACGAACCCGACAGCAAACA
GTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10510.86 Da
• Isoelectric Point: 4.3322

>AT187150 WP_202107597.1 NZ_CP068345:c1364110-1363829 [Succinivibrio dextrinosolvens]
MATSSINIRVDEEVKKNANILFNKLGLNMSTAINIFLQMSINQNGLPFKVSLNYNDDSLKAFEEADDIAKNPEKYKSYNS
FDELMEEVLGKDA

Nucleotide

• Length: 282 bp

>AT187150 NZ_CP089778:c2987049-2986804 [Mycobacterium tuberculosis]
ATGAGCGGCCACGCGTTGGCTGCTCGGACGTTGCTGGCCGCCGCGGACGAGCTTGTCGGCGGCCCGCCAGTCGAGGCTTC
GGCCGCCGCGCTGGCCGGCGACGCCGCGGGCGCATGGCGGACCGCGGCCGTCGAGCTTGCGCGAGCGTTGGTCCGCGCTG
TGGCGGAGTCGCACGGCGTCGCGGCCGTTTTGTTCGCCGCGACGGCCGCCGCGGCGGCGGCCGTCGACCGGGGTGATCCG
CCGTGA