Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 1427526..1428136 Replicon plasmid pRscUGMSS_Db01
Accession NZ_CP068286
Organism Ralstonia syzygii subsp. celebesensis strain UGMSS_Db01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JK151_RS22850 Protein ID WP_078223783.1
Coordinates 1427828..1428136 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JK151_RS22845 Protein ID WP_013209163.1
Coordinates 1427526..1427831 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JK151_RS22815 1422917..1423201 - 285 WP_078223782.1 hypothetical protein -
JK151_RS22820 1423534..1423721 + 188 Protein_1295 transposase -
JK151_RS22825 1423888..1424557 + 670 Protein_1296 hypothetical protein -
JK151_RS22830 1424662..1425165 - 504 Protein_1297 MFS transporter -
JK151_RS22835 1425259..1426469 + 1211 WP_099091583.1 IS3 family transposase -
JK151_RS22840 1426500..1427315 - 816 Protein_1299 MFS transporter -
JK151_RS22845 1427526..1427831 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
JK151_RS22850 1427828..1428136 - 309 WP_078223783.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JK151_RS22855 1428221..1429420 - 1200 WP_013209165.1 MFS transporter -
JK151_RS22860 1429548..1430363 - 816 WP_013209166.1 GntR family transcriptional regulator -
JK151_RS22865 1430537..1431088 - 552 WP_078223784.1 helix-turn-helix transcriptional regulator -
JK151_RS22870 1431220..1431814 + 595 Protein_1305 GNAT family N-acetyltransferase -
JK151_RS22875 1432071..1432505 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cheB / cheW / motA / katA / acrB / cheY 1..1614911 1614911


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11821.56 Da        Isoelectric Point: 9.0017

>T187134 WP_078223783.1 NZ_CP068286:c1428136-1427828 [Ralstonia syzygii subsp. celebesensis]
MLTIRTTEIFDDWFYSLRDKAAQRRVQVRIDRLQMGNPGDVKTVREGIREMRIDHGPGYRVYVAQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T187134 NZ_CP089778:1968440-1968688 [Mycobacterium tuberculosis]
ATGGTGATCGATACCTCTGCGCTGGTCGCGATGCTCAACGATGAACCCGAGGCGCAACGGTTCGAGATAGCCGTGGCAGC
AGACCACGTTTGGCTGATGTCGACGGCGTCATATCCGGAGATGGCGACCGTGATCGAAACACGCTTCGGGGAACCGGGGG
GACGTGAACCCAAGGTCAGCGGCCAGCCTCTCCTCTATAAGGGTGACGATTTCGCATGTATCGATATTCGCGCGGTTCTC
GCCGGCTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT187134 WP_013209163.1 NZ_CP068286:c1427831-1427526 [Ralstonia syzygii subsp. celebesensis]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT187134 NZ_CP089778:1968228-1968440 [Mycobacterium tuberculosis]
ATGGAATTGGCGGCTCGAATGGGCGAGACTTTGACACAAGCGGTCGTAGTTGCAGTGCGGGAGCAACTGGCCCGCCGGAC
CGGGCGCACCAGATCCATTTCGCTACGCGAGGAGTTGGCCGCCATTGGCCGGCGCTGCGCGGCCTTACCGGTGCTCGACA
CCCGAGCCGCGGACACGATTCTCGGCTACGACGAGCGCGGGTTGCCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References