187131

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2159364..2159904 Replicon chromosome
Accession NZ_CP068285
Organism Ralstonia syzygii subsp. celebesensis strain UGMSS_Db01

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JK151_RS10210 Protein ID WP_048817440.1
Coordinates 2159644..2159904 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JK151_RS10205 Protein ID WP_078221722.1
Coordinates 2159364..2159651 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JK151_RS10185 2155102..2156019 - 918 WP_078221725.1 MurR/RpiR family transcriptional regulator -
JK151_RS10190 2156186..2157475 + 1290 WP_078221724.1 FAD-dependent oxidoreductase -
JK151_RS10195 2157472..2158509 + 1038 WP_078221723.1 xylose isomerase -
JK151_RS10200 2158506..2159351 + 846 WP_013212795.1 TIM barrel protein -
JK151_RS10205 2159364..2159651 - 288 WP_078221722.1 putative addiction module antidote protein Antitoxin
JK151_RS10210 2159644..2159904 - 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JK151_RS10215 2160031..2160342 - 312 WP_048817439.1 Rieske 2Fe-2S domain-containing protein -
JK151_RS10220 2160308..2161456 - 1149 WP_078221721.1 fatty acid desaturase family protein -
JK151_RS10225 2161592..2162644 + 1053 WP_078221720.1 LacI family DNA-binding transcriptional regulator -
JK151_RS10230 2162854..2163771 + 918 WP_075464683.1 sugar ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T187131 WP_048817440.1 NZ_CP068285:c2159904-2159644 [Ralstonia syzygii subsp. celebesensis]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T187131 NZ_CP089778:1687290-1687607 [Mycobacterium tuberculosis]
GTGAACGCGCCGTTGCGTGGTCAGGTCTATCGATGCGACCTCGGATACGGGGCCAAACCGTGGCTCATCGTCTCCAACAA
CGCCCGCAACCGTCACACCGCCGACGTGGTGGCTGTGCGCCTGACAACAACGCGGAGAACCATACCGACCTGGGTCGCCA
TGGGCCCCAGCGATCCATTGACCGGATACGTCAACGCGGACAACATCGAGACCCTCGGCAAAGACGAGCTCGGTGACTAC
CTCGGTGAGGTCACGCCGGCGACGATGAACAAAATCAACACGGCGCTCGCGACCGCGCTGGGGCTACCGTGGCCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 9969.40 Da        Isoelectric Point: 4.5183

>AT187131 WP_078221722.1 NZ_CP068285:c2159651-2159364 [Ralstonia syzygii subsp. celebesensis]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARACGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT187131 NZ_CP089778:1686991-1687293 [Mycobacterium tuberculosis]
GTGCCGTTTCTGGTTGCATTATCCGGTATCATCTCGGGCGTGCGTGATCATTCGATGACCGTGCGGCTCGACCAGCAAAC
TCGCCAGCGCCTGCAAGACATTGTGAAAGGCGGATACCGGAGCGCTAATGCGGCGATCGTCGACGCCATCAACAAGCGCT
GGGAGGCGCTACACGATGAGCAACTCGACGCCGCCTACGCGGCCGCGATCCATGACAATCCGGCGTACCCGTACGAGTCT
GAGGCCGAACGGAGCGCCGCGCGGGCCCGGCGCAACGCCAGGCAGCAGCGCTCGGCACAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References