186992

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 2262145..2262650 Replicon chromosome
Accession NZ_CP068278
Organism Corynebacterium aquatimens strain CNCTC

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag JKI95_RS11580 Protein ID WP_234949082.1
Coordinates 2262396..2262650 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JKI95_RS11575 Protein ID WP_234947127.1
Coordinates 2262145..2262396 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKI95_RS11540 2257595..2258080 + 486 WP_284522846.1 hypothetical protein -
JKI95_RS11545 2258125..2258588 + 464 Protein_2245 methyltransferase -
JKI95_RS11550 (JKI95_11145) 2258600..2259247 - 648 WP_234947131.1 ABC transporter ATP-binding protein -
JKI95_RS11555 (JKI95_11150) 2259247..2260226 - 980 Protein_2247 ABC transporter permease -
JKI95_RS11560 2260355..2260702 + 348 WP_284522847.1 hypothetical protein -
JKI95_RS11565 (JKI95_11155) 2260660..2261472 + 813 WP_284522848.1 histidine kinase -
JKI95_RS11570 (JKI95_11160) 2261472..2262069 + 598 Protein_2250 response regulator transcription factor -
JKI95_RS11575 (JKI95_11165) 2262145..2262396 + 252 WP_234947127.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JKI95_RS11580 (JKI95_11170) 2262396..2262650 + 255 WP_234949082.1 Txe/YoeB family addiction module toxin Toxin
JKI95_RS11585 (JKI95_11175) 2262651..2263375 - 725 Protein_2253 NAD-dependent deacylase -
JKI95_RS11590 (JKI95_11180) 2263378..2263815 - 438 WP_284522849.1 thermonuclease family protein -
JKI95_RS11595 (JKI95_11185) 2263755..2264072 - 318 WP_284522850.1 hypothetical protein -
JKI95_RS11600 (JKI95_11190) 2264094..2264810 - 717 WP_284522851.1 DUF1648 domain-containing protein -
JKI95_RS11605 (JKI95_11195) 2264973..2265728 - 756 WP_234947123.1 peroxide stress protein YaaA -
JKI95_RS11610 (JKI95_11200) 2265760..2267559 + 1800 WP_234947122.1 proline--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10247.69 Da        Isoelectric Point: 7.3138

>T186992 WP_234949082.1 NZ_CP068278:2262396-2262650 [Corynebacterium aquatimens]
MHLVWDLNAWEDYTYWQNEDRKTLKRINQLLKDMLRDPFEGIGKPEPLKYGAEGAWSRRITQEHRLVYLVEGRDLVILQA
RYHY

Download         Length: 255 bp

>T186992 NZ_CP089776:c449260-448667 [Mycobacterium tuberculosis]
GTGAAGCGGCTCGATCTGGTCGCCGGGCCCAACGGCGCCGGCAAGTCGACGTTCGTCGCCCTCACGCTGGCGCCCTTGCT
GCCCGGCATCGTCTTCGTCAACGCCGACGAAATCGCCAAACAACGCTGGCCCGACGACCCAACATCGCACGCCTACCAGG
CGGCGCAGGTCGCCGCCGACACCCGCGCGAGGCTCATCGACTTGGGCCGGCCGTTCATTGCCGAGACGGTGTTCTCGCAC
CCATCGAAGCTCGAGCTCATCCGCACCGCGCGCACGGCCGGCTACACCGTCGTACTGCACGTGTTGGTTATCCCCGAAGG
CCTGGCGGTCGAGCGCGTCAGGCATCGCGTCGCCGCGGGCGGCCACGATGTGCCGGAGACCAAGATCCGCGAGCGTCACC
GCCGGCTGGCCGAGCTTGTCGCCCAGGCCATCACGCTGGCCGACGGCGCCACCGTCTATGACAACAGCCGGCTCGCGGGC
CCGCGGATCGTCGCTCAGTTCAGCGGGGGTGGCATCATCGGGCGCGCATGCTGGCCTTCGTGGACGCCGCCACCCTTGAT
GTCACGCTGGAGTAACAGGCCTGAGACGGCGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9494.55 Da        Isoelectric Point: 4.4915

>AT186992 WP_234947127.1 NZ_CP068278:2262145-2262396 [Corynebacterium aquatimens]
MTMSASEARRTFFPLLEQVNSDREAIEVASRHGNVVIMPADDYAAWVETAYLFRSPANARRLMESYENARAGRFEEHELD
LDA

Download         Length: 252 bp

>AT186992 NZ_CP089776:c449678-449289 [Mycobacterium tuberculosis]
GTGCCCAAAGCCGTCGACCGCGTCACGCGCGTCGCCGCGGATCTGGTGGACAGCGCGGCGGCCGAGGGTGCTCGTCAGAG
CCGTTCGGCCAAGCAGCAGCTCGACCACTGGGCCCGCGTCGGTCGGGCGGTGTCGAACCAGCACACGGCGTCGCGGCGCC
GCGTGGAAGCTGCGCTCGCGGGGCATCTGCCGATGACGGACCTGACGCTGGAGGAGGGCGTGGTGTTCAACGCCGAGATC
TCCGCAGCTATCGAGGAGCGCCTGTCGCGAACCAACTACGGCGACGTGCTCGCCGCGCAGGGCATCACCACGGTCGCCCT
GAACGACGCGGGCGACATCGTCGAGCACCGGCCAGACGGCACCTCGGTCGTGCTGGCGGCCACGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References