Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 5021700..5023381 Replicon chromosome
Accession NZ_CP068237
Organism Klebsiella quasipneumoniae strain YDKL-002

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag JJQ56_RS24100 Protein ID WP_202024227.1
Coordinates 5021700..5022617 (-) Length 306 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag JJQ56_RS24105 Protein ID WP_202024228.1
Coordinates 5022623..5023381 (-) Length 253 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJQ56_RS24080 5017006..5018526 + 1521 WP_202024225.1 sugar ABC transporter ATP-binding protein -
JJQ56_RS24085 5018523..5019521 + 999 WP_031592479.1 ribose ABC transporter permease -
JJQ56_RS24090 5019552..5020493 + 942 WP_008807254.1 ABC transporter substrate-binding protein -
JJQ56_RS24095 5020568..5021575 + 1008 WP_202024226.1 carbohydrate kinase family protein -
JJQ56_RS24100 5021700..5022617 - 918 WP_202024227.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
JJQ56_RS24105 5022623..5023381 - 759 WP_202024228.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
JJQ56_RS24110 5023467..5024195 - 729 WP_153679934.1 response regulator transcription factor -
JJQ56_RS24115 5024468..5026615 + 2148 WP_077598907.1 formate dehydrogenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-278)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-93)


Sequences

Toxin        


Download         Length: 306 a.a.        Molecular weight: 34632.07 Da        Isoelectric Point: 5.4707

>T186933 WP_202024227.1 NZ_CP068237:c5022617-5021700 [Klebsiella quasipneumoniae]
MDIQAPYYRQVALLMQVLPYVAVEREFALKGGTAINLFIRDFPRLSVDIDLAWVPLESRAIALPHIRDALARIAANLQQQ
AGMSAVLQANRSDEMRVIVTTDSAQIKIEVSPVARGTLYPPQEREVVGAVEDVFGYASLPVVSLPDLYGGKLCAALDRQH
PRDFYDVKLLLDAQELDRPIFNGFIAYLLSHNRPLAEVLSPRWKDIAEPFYREFSGMTFETIALEELTAVPNRMIDALKS
CFTQQDVDFLLSFKRGEPDWRLAPEMRIQDLPAVQWKLRNIHQMPAIKRAESLAKLEKVLAEWRS

Download         Length: 918 bp

>T186933 NZ_CP089775:c448415-447822 [Mycobacterium tuberculosis]
GTGAAGCGGCTCGATCTGGTCGCCGGGCCCAACGGCGCCGGCAAGTCGACGTTCGTCGCCCTCACGCTGGCGCCCTTGCT
GCCCGGCATCGTCTTCGTCAACGCCGACGAAATCGCCAAACAACGCTGGCCCGACGACCCAACATCGCACGCCTACCAGG
CGGCGCAGGTCGCCGCCGACACCCGCGCGAGGCTCATCGACTTGGGCCGGCCGTTCATTGCCGAGACGGTGTTCTCGCAC
CCATCGAAGCTCGAGCTCATCCGCACCGCGCGCACGGCCGGCTACACCGTCGTACTGCACGTGTTGGTTATCCCCGAAGG
CCTGGCGGTCGAGCGCGTCAGGCATCGCGTCGCCGCGGGCGGCCACGATGTGCCGGAGACCAAGATCCGCGAGCGTCACC
GCCGGCTGGCCGAGCTTGTCGCCCAGGCCATCACGCTGGCCGACGGCGCCACCGTCTATGACAACAGCCGGCTCGCGGGC
CCGCGGATCGTCGCTCAGTTCAGCGGGGGTGGCATCATCGGGCGCGCATGCTGGCCTTCGTGGACGCCGCCACCCTTGAT
GTCACGCTGGAGTAACAGGCCTGAGACGGCGTAA

Antitoxin


Download         Length: 253 a.a.        Molecular weight: 28534.93 Da        Isoelectric Point: 10.0007

>AT186933 WP_202024228.1 NZ_CP068237:c5023381-5022623 [Klebsiella quasipneumoniae]
MPTKLNWLLQNSAPGDVILQSWLSQHAISPSLAFKYKQSGWLTKLGSGVYARAGRKPEWSDALACLQNQLAAPVYVAGLS
SLVWQGRSHYLQLKQNQCWLSIENKTLLPKWFREFPGVEWIVISGQKLPVLDDKYRVTLDVKGKKLTGSAPELAAYELLS
AIPGTISFDHAAELFQGLVNLNPHKVEYLLSVSQSVQTKRLYLFFASFYEHAWLRRIDSQKIDLGAGKRQIVVNGKFNAQ
YQITVPERFQKE

Download         Length: 759 bp

>AT186933 NZ_CP089775:c448833-448444 [Mycobacterium tuberculosis]
GTGCCCAAAGCCGTCGACCGCGTCACGCGCGTCGCCGCGGATCTGGTGGACAGCGCGGCGGCCGAGGGTGCTCGTCAGAG
CCGTTCGGCCAAGCAGCAGCTCGACCACTGGGCCCGCGTCGGTCGGGCGGTGTCGAACCAGCACACGGCGTCGCGGCGCC
GCGTGGAAGCTGCGCTCGCGGGGCATCTGCCGATGACGGACCTGACGCTGGAGGAGGGCGTGGTGTTCAACGCCGAGATC
TCCGCAGCTATCGAGGAGCGCCTGTCGCGAACCAACTACGGCGACGTGCTCGCCGCGCAGGGCATCACCACGGTCGCCCT
GAACGACGCGGGCGACATCGTCGAGCACCGGCCAGACGGCACCTCGGTCGTGCTGGCGGCCACGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References