Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
| Location | 4660959..4662681 | Replicon | chromosome |
| Accession | NZ_CP068229 | ||
| Organism | Shewanella algae strain 150735 | ||
Toxin (Protein)
| Gene name | mosT | Uniprot ID | - |
| Locus tag | JKK46_RS20670 | Protein ID | WP_116546163.1 |
| Coordinates | 4660959..4661897 (-) | Length | 313 a.a. |
Antitoxin (Protein)
| Gene name | mosA | Uniprot ID | - |
| Locus tag | JKK46_RS20675 | Protein ID | WP_208129583.1 |
| Coordinates | 4661890..4662681 (-) | Length | 264 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JKK46_RS20655 (JKK46_20660) | 4657636..4659474 | - | 1839 | WP_208128692.1 | DNA methyltransferase | - |
| JKK46_RS20660 (JKK46_20665) | 4659455..4660486 | - | 1032 | WP_044733679.1 | IS630-like element ISSen5 family transposase | - |
| JKK46_RS20665 (JKK46_20670) | 4660570..4660920 | - | 351 | WP_208128693.1 | hypothetical protein | - |
| JKK46_RS20670 (JKK46_20675) | 4660959..4661897 | - | 939 | WP_116546163.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| JKK46_RS20675 (JKK46_20680) | 4661890..4662681 | - | 792 | WP_208129583.1 | type IV toxin-antitoxin system AbiEi family antitoxin | Antitoxin |
| JKK46_RS20680 (JKK46_20685) | 4662950..4664644 | + | 1695 | WP_208128694.1 | DUF927 domain-containing protein | - |
| JKK46_RS20685 (JKK46_20690) | 4664641..4664925 | + | 285 | WP_208128695.1 | helix-turn-helix domain-containing protein | - |
| JKK46_RS20690 (JKK46_20695) | 4664926..4665150 | + | 225 | WP_047732839.1 | hypothetical protein | - |
| JKK46_RS20695 (JKK46_20700) | 4665470..4666585 | - | 1116 | WP_208128696.1 | multidrug effflux MFS transporter | - |
| JKK46_RS20700 (JKK46_20705) | 4666740..4667516 | + | 777 | WP_208128697.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4653870..4664644 | 10774 | |
| - | flank | IS/Tn | - | - | 4659455..4660486 | 1031 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 313 a.a. Molecular weight: 35415.55 Da Isoelectric Point: 4.7004
>T186898 WP_116546163.1 NZ_CP068229:c4661897-4660959 [Shewanella algae]
MDRESPYYKQVSLLIRMLPVVATEPSFALKGGTAINLFVRDFPRLSVDIDLAYLPLEPRNEALANVKAALQRITDLINKE
PENQAVLQDHRLDELRIVVTSPNATIKIEVSPVARGTLHKPDSLPVQESVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVRMLLAEEGISRDIFVGFITYVLSHPRPINEVMAPNWQPLDDKFQAEFDGMTFEPVELNDLISIRPAMVAALQA
HFTEKDRSFLLSFKQGNPDWSLFDYPDASELPAIRWKLQNIAKLAKNQEKHVEQLTKLESVLDEWLKQANTN
MDRESPYYKQVSLLIRMLPVVATEPSFALKGGTAINLFVRDFPRLSVDIDLAYLPLEPRNEALANVKAALQRITDLINKE
PENQAVLQDHRLDELRIVVTSPNATIKIEVSPVARGTLHKPDSLPVQESVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVRMLLAEEGISRDIFVGFITYVLSHPRPINEVMAPNWQPLDDKFQAEFDGMTFEPVELNDLISIRPAMVAALQA
HFTEKDRSFLLSFKQGNPDWSLFDYPDASELPAIRWKLQNIAKLAKNQEKHVEQLTKLESVLDEWLKQANTN
Download Length: 939 bp
>T186898 NZ_CP089774:c1942527-1942138 [Mycobacterium tuberculosis]
GTGATCGTGTTGGACGCCTCGGCGGCCGTCGAGCTCATGCTCACGACGCCGGCGGGTGCGGCGGTCGCCCGGCGCTTGCG
GGGCGAAACCGTGCACGCCCCTGCACATTTCGATGTCGAGGTGATCGGGGCGATACGTCAAGCGGTCGTGCGTCAGCTGA
TCAGCGATCATGAAGGACTCGTCGTGGTTGTCAACTTCCTTAGCCTGCCCGTTCGGCGTTGGCCGTTAAAGCCATTCACC
CAGCGTGCCTACCAACTTCGGTCCACTCATACCGTGGCCGATGGAGCCTACGTCGCCCTCGCCGAGGGCCTCGGCGTACC
GCTTATCACTTGCGACGGGCGACTTGCCCAATCCCATGGCCATAATGCGGAGATCGAGCTTGTCGCCTGA
GTGATCGTGTTGGACGCCTCGGCGGCCGTCGAGCTCATGCTCACGACGCCGGCGGGTGCGGCGGTCGCCCGGCGCTTGCG
GGGCGAAACCGTGCACGCCCCTGCACATTTCGATGTCGAGGTGATCGGGGCGATACGTCAAGCGGTCGTGCGTCAGCTGA
TCAGCGATCATGAAGGACTCGTCGTGGTTGTCAACTTCCTTAGCCTGCCCGTTCGGCGTTGGCCGTTAAAGCCATTCACC
CAGCGTGCCTACCAACTTCGGTCCACTCATACCGTGGCCGATGGAGCCTACGTCGCCCTCGCCGAGGGCCTCGGCGTACC
GCTTATCACTTGCGACGGGCGACTTGCCCAATCCCATGGCCATAATGCGGAGATCGAGCTTGTCGCCTGA
Antitoxin
Download Length: 264 a.a. Molecular weight: 29946.06 Da Isoelectric Point: 9.5357
>AT186898 WP_208129583.1 NZ_CP068229:c4662681-4661890 [Shewanella algae]
MSSKINWLVANTYPGALVLQQWLTENGISYSLAQKYAQSGWLRKLSSGVYYRPSAKDDVKPGWVDALQAMDTQLHHPVHL
AGLSSLTHQGLSHYLQLSKEQVWIGVKNKQSLPKWFREFPNQNWFYCGNHKLEAVSEKDLKVITVKGKELKASCPELAAY
EVVDAIGKQISFEHAAELFQGLVNLSPRKVQSLLERSSSVQTNRVFLFLSHYHGHQWTQRIDETKIALGSGKRQVVEQGR
FDERYQITVPEILRVKQEDANNG
MSSKINWLVANTYPGALVLQQWLTENGISYSLAQKYAQSGWLRKLSSGVYYRPSAKDDVKPGWVDALQAMDTQLHHPVHL
AGLSSLTHQGLSHYLQLSKEQVWIGVKNKQSLPKWFREFPNQNWFYCGNHKLEAVSEKDLKVITVKGKELKASCPELAAY
EVVDAIGKQISFEHAAELFQGLVNLSPRKVQSLLERSSSVQTNRVFLFLSHYHGHQWTQRIDETKIALGSGKRQVVEQGR
FDERYQITVPEILRVKQEDANNG
Download Length: 792 bp
>AT186898 NZ_CP089774:c1942751-1942524 [Mycobacterium tuberculosis]
ATGTCCGCCATGGTTCAGATCCGCAACGTTCCCGACGAGCTTCTCCACGAGCTGAAGGCCCGCGCAGCGGCGCAACGGAT
GAGCCTGAGCGATTTCCTCCTAGCACGGCTTGCCGAGATCGCGGAAGAACCGGCCCTCGACGACGTTCTCGACCGTCTAG
CGGCACTGCCGCGCCGGGATCTCGGCGCGAGCGCAGCCGAGCTTGTTGACGAGGCTCGATCTGAGTGA
ATGTCCGCCATGGTTCAGATCCGCAACGTTCCCGACGAGCTTCTCCACGAGCTGAAGGCCCGCGCAGCGGCGCAACGGAT
GAGCCTGAGCGATTTCCTCCTAGCACGGCTTGCCGAGATCGCGGAAGAACCGGCCCTCGACGACGTTCTCGACCGTCTAG
CGGCACTGCCGCGCCGGGATCTCGGCGCGAGCGCAGCCGAGCTTGTTGACGAGGCTCGATCTGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|