186890

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3427128..3427770 Replicon chromosome
Accession NZ_CP068227
Organism Shewanella algae strain A59

Toxin (Protein)


Gene name ygfX Uniprot ID A0A5N5U1D5
Locus tag JKK33_RS15240 Protein ID WP_025010549.1
Coordinates 3427128..3427550 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag JKK33_RS15245 Protein ID WP_208126214.1
Coordinates 3427531..3427770 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKK33_RS15215 (JKK33_15215) 3422646..3423125 - 480 WP_208124981.1 SoxR reducing system RseC family protein -
JKK33_RS15220 (JKK33_15220) 3423136..3424068 - 933 WP_025887844.1 MucB/RseB C-terminal domain-containing protein -
JKK33_RS15225 (JKK33_15225) 3424078..3424698 - 621 WP_159352951.1 RseA family anti-sigma factor -
JKK33_RS15230 (JKK33_15230) 3424723..3425301 - 579 WP_025010551.1 RNA polymerase sigma factor RpoE -
JKK33_RS15235 (JKK33_15235) 3425500..3427110 + 1611 WP_025010550.1 L-aspartate oxidase -
JKK33_RS15240 (JKK33_15240) 3427128..3427550 - 423 WP_025010549.1 protein YgfX Toxin
JKK33_RS15245 (JKK33_15245) 3427531..3427770 - 240 WP_208126214.1 succinate dehydrogenase assembly factor 2 Antitoxin
JKK33_RS15250 (JKK33_15250) 3427869..3428777 - 909 WP_025010548.1 transcriptional activator NhaR -
JKK33_RS15255 (JKK33_15255) 3428794..3429177 - 384 WP_062793820.1 hypothetical protein -
JKK33_RS15260 (JKK33_15260) 3429174..3430349 - 1176 WP_025010547.1 Na+/H+ antiporter NhaA -
JKK33_RS15265 (JKK33_15265) 3430466..3431260 - 795 WP_208124982.1 thymidylate synthase -
JKK33_RS15270 (JKK33_15270) 3431260..3432087 - 828 WP_093982518.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-135)

Antitoxin

Flavinator of succinate dehydrogenase

(5-75)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16309.86 Da        Isoelectric Point: 7.0359

>T186890 WP_025010549.1 NZ_CP068227:c3427550-3427128 [Shewanella algae]
VAGQRHRFQLSSSFSQYLSLTVLAAICLSSFLAWPALDYPFYLLFKYLCLLLMLAGFGLALWRLRCWQLCFWLNELGEGQ
FEPGSSFELSGRPWVSPFVVTFTYQGEDNYGRCWLFADMFDDTDYRHLCRLLLQRSKSAN

Download         Length: 423 bp

>T186890 NZ_CP089774:c1237833-1237522 [Mycobacterium tuberculosis]
ATGCGACCTATCCACATCGCACAGCTTGACAAGGCTAGACCCGTCCTGATCCTTACCCGCGAGGTCGTACGTCCGCACCT
CACGAACGTCACCGTCGCCCCGATCACGACAACCGTGCGTGGGCTAGCCACCGAAGTCCCGGTAGACGCGGTGAACGGGC
TGAATCAACCGTCAGTCGTCAGCTGCGACAACACCCAAACGATCCCGGTGTGTGACCTTGGTCGTCAAATCGGCTACCTG
CTCGCGTCGCAGGAGCCGGCTCTAGCCGAGGCCATCGGCAACGCGTTCGACCTCGATTGGGTGGTGGCATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9278.75 Da        Isoelectric Point: 5.0633

>AT186890 WP_208126214.1 NZ_CP068227:c3427770-3427531 [Shewanella algae]
MSTPRVKWACRRGMLELDVLFQPFVEQHYETLSPEDKALFVRLLECEDPELFAWFMGHEQCQDPQLAQMVVRVRGRAAP

Download         Length: 240 bp

>AT186890 NZ_CP089774:c1238153-1237833 [Mycobacterium tuberculosis]
ATGTACCTACCCTGGGGGGTCGTCCTCGCCGGCGGCGCGAACGGTTTTGGGGCGGGTGCATACCAAACTGGTACCATCTG
TGAAGTGAGTACACAGATTGCGGTTCGCTTGCCCGATGAGATTGTCGCGTTCATCGACGACGAAGTCCGGGGACAGCATG
CCCGTAGCCGTGCGGCTGTCGTGCTGCGGGCGCTGGAACGGGAACGCCGCCGTCGTCTCGCCGAACGCGACGCGGAGATC
CTCGCCACCAACACGTCAGCCACGGGTGATCTGGATACGCTGGCCGGCCACTGCGCTCGTACCGCCCTCGACATCGACTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References