Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tsbAT/- |
| Location | 665914..666717 | Replicon | chromosome |
| Accession | NZ_CP068216 | ||
| Organism | Staphylococcus pasteuri strain FDAARGOS_1152 | ||
Toxin (Protein)
| Gene name | tsbT | Uniprot ID | - |
| Locus tag | I6J09_RS03050 | Protein ID | WP_017638030.1 |
| Coordinates | 665914..666090 (-) | Length | 59 a.a. |
Antitoxin (Protein)
| Gene name | tsbA | Uniprot ID | A0A654BAN2 |
| Locus tag | I6J09_RS03055 | Protein ID | WP_017638029.1 |
| Coordinates | 666118..666717 (-) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J09_RS03025 (I6J09_03020) | 661003..661626 | - | 624 | WP_029056287.1 | response regulator transcription factor | - |
| I6J09_RS03030 (I6J09_03025) | 661647..662759 | - | 1113 | WP_208969977.1 | GAF domain-containing sensor histidine kinase | - |
| I6J09_RS03035 (I6J09_03030) | 662939..663769 | + | 831 | WP_029056289.1 | RluA family pseudouridine synthase | - |
| I6J09_RS03040 (I6J09_03035) | 663829..665214 | - | 1386 | WP_046466851.1 | class II fumarate hydratase | - |
| I6J09_RS03045 (I6J09_03040) | 665370..665762 | - | 393 | WP_017638031.1 | hypothetical protein | - |
| I6J09_RS03050 (I6J09_03045) | 665914..666090 | - | 177 | WP_017638030.1 | SAS053 family protein | Toxin |
| I6J09_RS03055 (I6J09_03050) | 666118..666717 | - | 600 | WP_017638029.1 | glucosamine-6-phosphate isomerase | Antitoxin |
| I6J09_RS03060 (I6J09_03055) | 666899..667369 | - | 471 | WP_119623037.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
| I6J09_RS03065 (I6J09_03060) | 667370..668500 | - | 1131 | WP_046466852.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
| I6J09_RS03070 (I6J09_03065) | 668643..669365 | - | 723 | WP_046466853.1 | amino acid ABC transporter ATP-binding protein | - |
| I6J09_RS03075 (I6J09_03070) | 669358..670818 | - | 1461 | WP_107999718.1 | ABC transporter substrate-binding protein/permease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6787.12 Da Isoelectric Point: 3.8537
>T186874 WP_017638030.1 NZ_CP068216:c666090-665914 [Staphylococcus pasteuri]
MTQNKDSKTNYHEEENAMVTDLDDLKDLGKEMEQISEENDEDKLNQSHDSDVRSDLEE
MTQNKDSKTNYHEEENAMVTDLDDLKDLGKEMEQISEENDEDKLNQSHDSDVRSDLEE
Download Length: 177 bp
>T186874 NZ_CP089774:c448416-447823 [Mycobacterium tuberculosis]
GTGAAGCGGCTCGATCTGGTCGCCGGGCCCAACGGCGCCGGCAAGTCGACGTTCGTCGCCCTCACGCTGGCGCCCTTGCT
GCCCGGCATCGTCTTCGTCAACGCCGACGAAATCGCCAAACAACGCTGGCCCGACGACCCAACATCGCACGCCTACCAGG
CGGCGCAGGTCGCCGCCGACACCCGCGCGAGGCTCATCGACTTGGGCCGGCCGTTCATTGCCGAGACGGTGTTCTCGCAC
CCATCGAAGCTCGAGCTCATCCGCACCGCGCGCACGGCCGGCTACACCGTCGTACTGCACGTGTTGGTTATCCCCGAAGG
CCTGGCGGTCGAGCGCGTCAGGCATCGCGTCGCCGCGGGCGGCCACGATGTGCCGGAGACCAAGATCCGCGAGCGTCACC
GCCGGCTGGCCGAGCTTGTCGCCCAGGCCATCACGCTGGCCGACGGCGCCACCGTCTATGACAACAGCCGGCTCGCGGGC
CCGCGGATCGTCGCTCAGTTCAGCGGGGGTGGCATCATCGGGCGCGCATGCTGGCCTTCGTGGACGCCGCCACCCTTGAT
GTCACGCTGGAGTAACAGGCCTGAGACGGCGTAA
GTGAAGCGGCTCGATCTGGTCGCCGGGCCCAACGGCGCCGGCAAGTCGACGTTCGTCGCCCTCACGCTGGCGCCCTTGCT
GCCCGGCATCGTCTTCGTCAACGCCGACGAAATCGCCAAACAACGCTGGCCCGACGACCCAACATCGCACGCCTACCAGG
CGGCGCAGGTCGCCGCCGACACCCGCGCGAGGCTCATCGACTTGGGCCGGCCGTTCATTGCCGAGACGGTGTTCTCGCAC
CCATCGAAGCTCGAGCTCATCCGCACCGCGCGCACGGCCGGCTACACCGTCGTACTGCACGTGTTGGTTATCCCCGAAGG
CCTGGCGGTCGAGCGCGTCAGGCATCGCGTCGCCGCGGGCGGCCACGATGTGCCGGAGACCAAGATCCGCGAGCGTCACC
GCCGGCTGGCCGAGCTTGTCGCCCAGGCCATCACGCTGGCCGACGGCGCCACCGTCTATGACAACAGCCGGCTCGCGGGC
CCGCGGATCGTCGCTCAGTTCAGCGGGGGTGGCATCATCGGGCGCGCATGCTGGCCTTCGTGGACGCCGCCACCCTTGAT
GTCACGCTGGAGTAACAGGCCTGAGACGGCGTAA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22646.58 Da Isoelectric Point: 4.9933
>AT186874 WP_017638029.1 NZ_CP068216:c666717-666118 [Staphylococcus pasteuri]
MAMNFKVFEDKQRVAEYTADILRKQFNNNPMTIAGVHLTKDHAPVLDELKKNVELHAVDFSQINILDYDENKSYYEALGV
PQSQIYSLSYNQDANEFISDKIKTKENKGKLVLQVVSIDENGNLDVSVRQGLLEAREIFLVVTGSNKREVVEKLYNENGK
SNYEPADLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA
MAMNFKVFEDKQRVAEYTADILRKQFNNNPMTIAGVHLTKDHAPVLDELKKNVELHAVDFSQINILDYDENKSYYEALGV
PQSQIYSLSYNQDANEFISDKIKTKENKGKLVLQVVSIDENGNLDVSVRQGLLEAREIFLVVTGSNKREVVEKLYNENGK
SNYEPADLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA
Download Length: 600 bp
>AT186874 NZ_CP089774:c448834-448445 [Mycobacterium tuberculosis]
GTGCCCAAAGCCGTCGACCGCGTCACGCGCGTCGCCGCGGATCTGGTGGACAGCGCGGCGGCCGAGGGTGCTCGTCAGAG
CCGTTCGGCCAAGCAGCAGCTCGACCACTGGGCCCGCGTCGGTCGGGCGGTGTCGAACCAGCACACGGCGTCGCGGCGCC
GCGTGGAAGCTGCGCTCGCGGGGCATCTGCCGATGACGGACCTGACGCTGGAGGAGGGCGTGGTGTTCAACGCCGAGATC
TCCGCAGCTATCGAGGAGCGCCTGTCGCGAACCAACTACGGCGACGTGCTCGCCGCGCAGGGCATCACCACGGTCGCCCT
GAACGACGCGGGCGACATCGTCGAGCACCGGCCAGACGGCACCTCGGTCGTGCTGGCGGCCACGCCGTGA
GTGCCCAAAGCCGTCGACCGCGTCACGCGCGTCGCCGCGGATCTGGTGGACAGCGCGGCGGCCGAGGGTGCTCGTCAGAG
CCGTTCGGCCAAGCAGCAGCTCGACCACTGGGCCCGCGTCGGTCGGGCGGTGTCGAACCAGCACACGGCGTCGCGGCGCC
GCGTGGAAGCTGCGCTCGCGGGGCATCTGCCGATGACGGACCTGACGCTGGAGGAGGGCGTGGTGTTCAACGCCGAGATC
TCCGCAGCTATCGAGGAGCGCCTGTCGCGAACCAACTACGGCGACGTGCTCGCCGCGCAGGGCATCACCACGGTCGCCCT
GAACGACGCGGGCGACATCGTCGAGCACCGGCCAGACGGCACCTCGGTCGTGCTGGCGGCCACGCCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|