Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1071653..1072206 Replicon chromosome
Accession NZ_CP068211
Organism Achromobacter xylosoxidans strain FDAARGOS_1091

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6I48_RS04940 Protein ID WP_026384933.1
Coordinates 1071928..1072206 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6I48_RS04935 Protein ID WP_054482352.1
Coordinates 1071653..1071859 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I48_RS04920 1068292..1069269 - 978 WP_054482353.1 tripartite tricarboxylate transporter substrate binding protein -
I6I48_RS04925 1069461..1070111 - 651 WP_049052563.1 hypothetical protein -
I6I48_RS04930 1070110..1071555 + 1446 WP_047992431.1 RNA polymerase factor sigma-54 -
I6I48_RS04935 1071653..1071859 + 207 WP_054482352.1 hypothetical protein Antitoxin
I6I48_RS04940 1071928..1072206 + 279 WP_026384933.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6I48_RS04945 1072385..1072684 + 300 WP_006386990.1 (2Fe-2S)-binding protein -
I6I48_RS04950 1072654..1073574 - 921 WP_054482351.1 LysR family transcriptional regulator -
I6I48_RS04955 1073688..1074602 + 915 WP_054482350.1 DMT family transporter -
I6I48_RS04960 1075027..1075503 + 477 WP_006386993.1 bacterioferritin -
I6I48_RS04965 1075588..1076286 - 699 WP_026384932.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10369.93 Da        Isoelectric Point: 9.5759

>T186833 WP_026384933.1 NZ_CP068211:1071928-1072206 [Achromobacter xylosoxidans]
MLDVSWLQTAADDLAGIISYIAERSPQAARNLRQRIDNAVLSLARHPCRYRAGRVSGTRECVVHPNYVVVYRVTALAIEV
VNIVHARREYPP

Download         Length: 279 bp

>T186833 NZ_CP089773:1391745-1392176 [Mycobacterium tuberculosis]
GTGATCATCCCTGACATCAATCTGCTGCTCTACGCGGTCATCACCGGATTCCCGCAGCACCGGCGCGCGCATGCGTGGTG
GCAAGACACCGTCAACGGCCACACCCGTATCGGGCTGACGTATCCGGCGTTGTTCGGGTTCCTACGGATCGCCACCAGTG
CCCGCGTGCTCGCCGCGCCACTGCCAACCGCGGATGCGATCGCCTATGTGCGCGAGTGGCTTTCGCAGCCGAACGTGGAC
CTACTCACGGCGGGTCCGCGCCACCTGGACATCGCGTTGGGCCTGCTCGACAAGCTCGGCACAGCCAGCCACCTAACCAC
CGATGTGCAACTGGCCGCCTACGGCATCGAATACGACGCCGAGATCCATTCCAGTGACACCGACTTTGCCCGATTCGCCG
ATCTGAAGTGGACCGACCCGTTGCGCGAATAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7702.59 Da        Isoelectric Point: 4.5026

>AT186833 WP_054482352.1 NZ_CP068211:1071653-1071859 [Achromobacter xylosoxidans]
MGPIPSSILSEFETEEQAVSYDRWFRAKVQASLDDPRPAVSHQRVMARIDAIIETACRRQLDPQDGES

Download         Length: 207 bp

>AT186833 NZ_CP089773:1391488-1391748 [Mycobacterium tuberculosis]
ATGCGCACCACCTTGACGCTCGATGACGACGTCGTCCGGCTGGTCGAAGACGCAGTGCATCGCGAACGCCGCCCGATGAA
GCAGGTCATCAACGATGCGCTGCGCAGAGCGCTGGCGCCGCCGGTGAAACGGCAGGAGCAGTATCGGTTGGAGCCGCATG
AGTCGGCTGTGCGTTCCGGGTTGGATCTGGCCGGCTTCAACAAGTTGGCCGACGAACTGGAGGATGAGGCGCTGCTGGAT
GCCACGCGTCGGGCCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References