Detailed information of TA system TA186831

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 668978..669627
• Replicon: chromosome
• Accession: NZ_CP068206
• Organism: Acinetobacter johnsonii strain FDAARGOS_1092

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9D0M9
• Locus tag: I6I49_RS05265
• Protein ID: WP_004977893.1
• Coordinates: 668978..669364 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9CU98
• Locus tag: I6I49_RS05270
• Protein ID: WP_004977895.1
• Coordinates: 669370..669627 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I49_RS05240	664311..666593	-	2283	WP_201952601.1	TRAP transporter large permease subunit	-
I6I49_RS05245	666776..667348	-	573	WP_201952604.1	rhombosortase	-
I6I49_RS05250	667420..667983	-	564	WP_078389879.1	hypothetical protein	-
I6I49_RS05255	667980..668222	-	243	WP_201952606.1	hypothetical protein	-
I6I49_RS05260	668677..668892	-	216	WP_201953972.1	hypothetical protein	-
I6I49_RS05265	668978..669364	-	387	WP_004977893.1	hypothetical protein	Toxin
I6I49_RS05270	669370..669627	-	258	WP_004977895.1	succinate dehydrogenase assembly factor 2	Antitoxin
I6I49_RS05275	669820..670992	+	1173	WP_201952609.1	acyl-CoA dehydrogenase family protein	-
I6I49_RS05280	671028..671819	-	792	WP_148825440.1	alpha/beta hydrolase	-
I6I49_RS05285	671957..673447	-	1491	WP_201952612.1	NAD(P)/FAD-dependent oxidoreductase	-
I6I49_RS05290	673643..674008	-	366	WP_004691290.1	50S ribosomal protein L17	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-127)

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15380.35 Da
• Isoelectric Point: 10.4419

>T186831 WP_004977893.1 NZ_CP068206:c669364-668978 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPFGLWLITLVAGFVLYLFFLRGPQHFQLQHLDGRDWSLSLQKQTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPITQWKALKILTKMQ

Nucleotide

• Length: 387 bp

>T186831 NZ_CP089773:c1237138-1236827 [Mycobacterium tuberculosis]
ATGCGACCTATCCACATCGCACAGCTTGACAAGGCTAGACCCGTCCTGATCCTTACCCGCGAGGTCGTACGTCCGCACCT
CACGAACGTCACCGTCGCCCCGATCACGACAACCGTGCGTGGGCTAGCCACCGAAGTCCCGGTAGACGCGGTGAACGGGC
TGAATCAACCGTCAGTCGTCAGCTGCGACAACACCCAAACGATCCCGGTGTGTGACCTTGGTCGTCAAATCGGCTACCTG
CTCGCGTCGCAGGAGCCGGCTCTAGCCGAGGCCATCGGCAACGCGTTCGACCTCGATTGGGTGGTGGCATAG

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10181.71 Da
• Isoelectric Point: 4.7119

>AT186831 WP_004977895.1 NZ_CP068206:c669627-669370 [Acinetobacter johnsonii]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT186831 NZ_CP089773:c1237458-1237138 [Mycobacterium tuberculosis]
ATGTACCTACCCTGGGGGGTCGTCCTCGCCGGCGGCGCGAACGGTTTTGGGGCGGGTGCATACCAAACTGGTACCATCTG
TGAAGTGAGTACACAGATTGCGGTTCGCTTGCCCGATGAGATTGTCGCGTTCATCGACGACGAAGTCCGGGGACAGCATG
CCCGTAGCCGTGCGGCTGTCGTGCTGCGGGCGCTGGAACGGGAACGCCGCCGTCGTCTCGCCGAACGCGACGCGGAGATC
CTCGCCACCAACACGTCAGCCACGGGTGATCTGGATACGCTGGCCGGCCACTGCGCTCGTACCGCCCTCGACATCGACTG
A

Structures

Toxin

• AlphaFold DB: N9D0M9

Antitoxin

• AlphaFold DB: N9CU98