Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/Doc(toxin) |
Location | 3037053..3037615 | Replicon | chromosome |
Accession | NZ_CP068187 | ||
Organism | Acinetobacter johnsonii strain FDAARGOS_1094 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | I6I51_RS15280 | Protein ID | WP_125280299.1 |
Coordinates | 3037223..3037615 (+) | Length | 131 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | I6I51_RS15275 | Protein ID | WP_125280298.1 |
Coordinates | 3037053..3037223 (+) | Length | 57 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6I51_RS15265 | 3033376..3034098 | - | 723 | WP_125280296.1 | folate-binding Fe/S cluster repair protein | - |
I6I51_RS15270 | 3034360..3036978 | + | 2619 | WP_201702571.1 | Fe/S-dependent 2-methylisocitrate dehydratase AcnD | - |
I6I51_RS15275 | 3037053..3037223 | + | 171 | WP_125280298.1 | acetyltransferase | Antitoxin |
I6I51_RS15280 | 3037223..3037615 | + | 393 | WP_125280299.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin |
I6I51_RS15285 | 3037798..3039561 | + | 1764 | WP_075695922.1 | AAA family ATPase | - |
I6I51_RS15290 | 3039669..3039812 | + | 144 | WP_004637424.1 | zinc ribbon-containing protein | - |
I6I51_RS15295 | 3040153..3040296 | + | 144 | WP_004695201.1 | zinc ribbon-containing protein | - |
I6I51_RS15300 | 3040415..3040990 | + | 576 | WP_201702572.1 | DUF4126 domain-containing protein | - |
I6I51_RS15305 | 3041223..3041429 | + | 207 | WP_004695205.1 | hypothetical protein | - |
I6I51_RS15310 | 3041511..3041864 | - | 354 | WP_201702573.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 131 a.a. Molecular weight: 14069.88 Da Isoelectric Point: 4.0582
>T186818 WP_125280299.1 NZ_CP068187:3037223-3037615 [Acinetobacter johnsonii]
MNIICFPFERVIEINAFILATEKGMKGASDVGKLQGALARVDNAIVYEGLDDVFEIAAKYASSIANAHALSDANKRTGLA
VALEYLSLNDYELLQDNELLADAVRDLVIGEVTENDFADILYAHYVANGG
MNIICFPFERVIEINAFILATEKGMKGASDVGKLQGALARVDNAIVYEGLDDVFEIAAKYASSIANAHALSDANKRTGLA
VALEYLSLNDYELLQDNELLADAVRDLVIGEVTENDFADILYAHYVANGG
Download Length: 393 bp
>T186818 NZ_CP089773:c699872-699480 [Mycobacterium tuberculosis]
GTGAACGTACGGCGCGCCCTCGCCGACACATCCGTTTTCATTGGCATCGAGGCGACACGATTCGACCCGGACCGGTTTGC
GGGATACGAATGGGGCGTCTCGGTAGTCACACTCGGCGAGCTGCGGCTCGGGGTGTTGCAAGCCTCCGGCCCCGAGGCCG
CCGCACGTCGGCTCTCCACCTACCAGCTTGCGCAACGGTTCGAACCACTAGGCATCGACGAGGCGGTCTCCGAAGCATGG
GCATTACTGGTGTCCAAGCTGCGCGCCGCCAAACTGCGCGTGCCGATCAACGACAGCTGGATTGCGGCCACAGCCGTGGC
GCACGGCATTGCGATCCTGACCCAAGACAACGACTACGCCGCCATGCCCGACGTCGAGGTCATAACGATCTGA
GTGAACGTACGGCGCGCCCTCGCCGACACATCCGTTTTCATTGGCATCGAGGCGACACGATTCGACCCGGACCGGTTTGC
GGGATACGAATGGGGCGTCTCGGTAGTCACACTCGGCGAGCTGCGGCTCGGGGTGTTGCAAGCCTCCGGCCCCGAGGCCG
CCGCACGTCGGCTCTCCACCTACCAGCTTGCGCAACGGTTCGAACCACTAGGCATCGACGAGGCGGTCTCCGAAGCATGG
GCATTACTGGTGTCCAAGCTGCGCGCCGCCAAACTGCGCGTGCCGATCAACGACAGCTGGATTGCGGCCACAGCCGTGGC
GCACGGCATTGCGATCCTGACCCAAGACAACGACTACGCCGCCATGCCCGACGTCGAGGTCATAACGATCTGA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6316.39 Da Isoelectric Point: 10.9041
>AT186818 WP_125280298.1 NZ_CP068187:3037053-3037223 [Acinetobacter johnsonii]
MNKKVEKYGVAAVERPKIQATKQLDLSGDTGRQIVKSETKLALRTHSKTFKRLADM
MNKKVEKYGVAAVERPKIQATKQLDLSGDTGRQIVKSETKLALRTHSKTFKRLADM
Download Length: 171 bp
>AT186818 NZ_CP089773:c700126-699869 [Mycobacterium tuberculosis]
ATGTCTGCTACGATACCCGCTCGCGATCTTCGCAACCACACCGCCGAGGTACTGCGGCGAGTTGCCGCCGGCGAGGAAAT
CGAGGTGCTCAAGGACAATCGCCCCGTAGCGCGCATCGTTCCGCTCAAGCGGCGCCGCCAATGGTTGCCAGCTGCCGAGG
TGATCGGCGAACTGGTGCGCTTGGGCCCCGATACCACCAATCTGGGCGAGGAGCTGCGAGAGACGCTGACGCAAACCACG
GACGATGTGCGGTGGTGA
ATGTCTGCTACGATACCCGCTCGCGATCTTCGCAACCACACCGCCGAGGTACTGCGGCGAGTTGCCGCCGGCGAGGAAAT
CGAGGTGCTCAAGGACAATCGCCCCGTAGCGCGCATCGTTCCGCTCAAGCGGCGCCGCCAATGGTTGCCAGCTGCCGAGG
TGATCGGCGAACTGGTGCGCTTGGGCCCCGATACCACCAATCTGGGCGAGGAGCTGCGAGAGACGCTGACGCAAACCACG
GACGATGTGCGGTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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