Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1790649..1791133 Replicon chromosome
Accession NZ_CP068170
Organism Erysipelatoclostridium ramosum strain FDAARGOS_1105

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6I62_RS08745 Protein ID WP_118264103.1
Coordinates 1790864..1791133 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6I62_RS08740 Protein ID WP_118264104.1
Coordinates 1790649..1790867 (+) Length 73 a.a.

Genomic Context

I6I62_RS08725I6I62_RS08730I6I62_RS08735I6I62_RS08740I6I62_RS08745I6I62_RS08750I6I62_RS08755I6I62_RS08760I6I62_RS08765I6I62_RS08770I6I62_RS08775
Location: 1787388..1788398 (1011 bp)
Type: Others
Protein ID: WP_201899501.1
Location: 1788479..1789297 (819 bp)
Type: Others
Protein ID: WP_118264106.1
Location: 1789435..1790586 (1152 bp)
Type: Others
Protein ID: WP_118264105.1
Location: 1790649..1790867 (219 bp)
Type: Antitoxin
Protein ID: WP_118264104.1
Location: 1790864..1791133 (270 bp)
Type: Toxin
Protein ID: WP_118264103.1
Location: 1791428..1792111 (684 bp)
Type: Others
Protein ID: WP_118264102.1
Location: 1792123..1792467 (345 bp)
Type: Others
Protein ID: WP_118264101.1
Location: 1793055..1793957 (903 bp)
Type: Others
Protein ID: WP_201899503.1
Location: 1794252..1794461 (210 bp)
Type: Others
Protein ID: WP_118264099.1
Location: 1794559..1795557 (999 bp)
Type: Others
Protein ID: WP_201899505.1
Location: 1795713..1796066 (354 bp)
Type: Others
Protein ID: WP_201899507.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6I62_RS087251787388..1788398+1011WP_201899501.1C40 family peptidase-
I6I62_RS087301788479..1789297+819WP_118264106.1hypothetical protein-
I6I62_RS087351789435..1790586+1152WP_118264105.1hypothetical protein-
I6I62_RS087401790649..1790867+219WP_118264104.1CopG family transcriptional regulatorAntitoxin
I6I62_RS087451790864..1791133+270WP_118264103.1type II toxin-antitoxin system RelE/ParE family toxinToxin
I6I62_RS087501791428..1792111+684WP_118264102.1hypothetical protein-
I6I62_RS087551792123..1792467+345WP_118264101.1hypothetical protein-
I6I62_RS087601793055..1793957+903WP_201899503.1hypothetical protein-
I6I62_RS087651794252..1794461+210WP_118264099.1hypothetical protein-
I6I62_RS087701794559..1795557+999WP_201899505.1NERD domain-containing protein-
I6I62_RS087751795713..1796066+354WP_201899507.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1786899..185896472065


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-70)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10573.40 Da        Isoelectric Point: 10.3360

>T186809 WP_118264103.1 NZ_CP068170:1790864-1791133 [Erysipelatoclostridium ramosum]
MRYKVVFSKTVLKQLKKMDKYTKLLLINWIENNLDGCDDPRVHGKALSANRSGQWRYRIGDYRLICEIEDNKLVIFALSV
GHRKDVYKR

Download         Length: 270 bp

>T186809 NZ_CP089772:c3791427-3791035 [Mycobacterium tuberculosis]
ATGGCGGCCATCTATCTCGACTCGTCCGCGATCGTCAAGCTCGCGGTTCGCGAGCCAGAGTCGGACGCGCTGCGCCGCTA
CCTTCGCACCCGCCACCCGCGAGTGTCGAGTGCCCTTGCGCGCGCGGAGGTCATGCGGGCCCTGCTTGACAAGGGTGAAT
CAGCGCGGAAAGCCGGCCGCCGGGCGCTGGCTCATCTCGATCTGCTGCGCGTCGACAAGCGCGTCCTCGATCTCGCTGGT
GGGCTGCTGCCATTCGAGCTGCGCACGCTCGATGCCATCCACTTGGCGACGGCGCAGCGGCTCGGCGTCGATCTGGGCCG
GTTGTGCACCTACGACGACCGGATGCGCGACGCCGCCAAGACGCTCGGCATGGCCGTGATCGCCCCGTCGTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8339.49 Da        Isoelectric Point: 4.4929

>AT186809 WP_118264104.1 NZ_CP068170:1790649-1790867 [Erysipelatoclostridium ramosum]
MSFSMRLSQEEESLFKSYAKLHGISLSEALKRALLEKIEDEYDINIAESAYKEYLKDPVTYSMDDVKKELGL

Download         Length: 219 bp

>AT186809 NZ_CP089772:c3791702-3791427 [Mycobacterium tuberculosis]
ATGACCTCGGTGGGGGTGCGTGCGCTGCGGCAGCGGGCCAGCGAGCTGCTGCGCCGAGTCGAGGCCGGCGAGACGATCGA
GATCACCGACCGCGGCCGGCCCGTCGCCCTGCTCTCGCCGCTGCCGCAGGGCGGTCCATACGAGCAGCTGCTGGCAAGCG
GCGAGATCGAGCGTGCCACGCTCGACGTCGTTGATCTGCCCGAACCGCTCGACCTCGACGCGGGCGTCGAGCTGCCGTCG
GTGACGCTTGCGCGCCTGCGTGAGCACGAGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References