Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 5709104..5709744 | Replicon | chromosome |
Accession | NZ_CP068151 | ||
Organism | Pseudomonas fluorescens strain FDAARGOS_1088 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | A0A0W0MYI4 |
Locus tag | I6I45_RS26030 | Protein ID | WP_014719602.1 |
Coordinates | 5709331..5709744 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | - |
Locus tag | I6I45_RS26025 | Protein ID | WP_103452516.1 |
Coordinates | 5709104..5709334 (+) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6I45_RS26005 | 5705362..5706321 | + | 960 | WP_014719606.1 | LysR family transcriptional regulator | - |
I6I45_RS26010 | 5706413..5707060 | - | 648 | WP_020303103.1 | HAD-IB family hydrolase | - |
I6I45_RS26015 | 5707133..5707306 | - | 174 | Protein_5120 | HNH endonuclease | - |
I6I45_RS26020 | 5707373..5708623 | - | 1251 | WP_014719604.1 | ribonucleotide-diphosphate reductase subunit beta | - |
I6I45_RS26025 | 5709104..5709334 | + | 231 | WP_103452516.1 | AbrB family transcriptional regulator | Antitoxin |
I6I45_RS26030 | 5709331..5709744 | + | 414 | WP_014719602.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
I6I45_RS26035 | 5709882..5710151 | - | 270 | WP_014719601.1 | DUF2790 domain-containing protein | - |
I6I45_RS26040 | 5710550..5712505 | + | 1956 | WP_127882265.1 | acetate--CoA ligase | - |
I6I45_RS26045 | 5713202..5713987 | + | 786 | WP_020302951.1 | ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 15188.53 Da Isoelectric Point: 7.6998
>T186764 WP_014719602.1 NZ_CP068151:5709331-5709744 [Pseudomonas fluorescens]
VTTYMLDTCICSFIMRERPECVLKRLALEVARSNRIVISAITYAEMRYGQIGKKASSKHKTLVDEFVKRLDEVLPWGVAA
VDATVEVKRSLTEQGAIIGQNDTAIAGHAIASGCTLVTNNIREFSRVAGLSYEDWVH
VTTYMLDTCICSFIMRERPECVLKRLALEVARSNRIVISAITYAEMRYGQIGKKASSKHKTLVDEFVKRLDEVLPWGVAA
VDATVEVKRSLTEQGAIIGQNDTAIAGHAIASGCTLVTNNIREFSRVAGLSYEDWVH
Download Length: 414 bp
>T186764 NZ_CP089772:718051-718446 [Mycobacterium tuberculosis]
ATGGTGATCGACACGTCCGCGCTCGTTGCGATGCTCAGCGACGAGCCAGACGCAGAGCGGTTCGAGGCCGCCGTCGAAGC
CGACCACATCCGGCTGATGTCGACGGCGTCTTACCTGGAAACGGCACTCGTGATAGAAGCCCGCTTCGGTGAACCGGGCG
GACGTGAGCTGGATCTGTGGCTTCATCGCGCCGCGGTCGACCTTGTTGCCGTGCATGCCGACCAAGCGGATGCCGCGCGC
GCCGCCTACCGCACGTACGGCAAGGGAAGGCATCGTGCGGGGCTCAACTACGGCGACTGCTTCTCATACGGCCTCGCCAA
GATCAGCGGCCAGCCACTCCTGTTCAAGGGCGAAGATTTCCAACACACCGACATCGCCACGGTCGCGCTGCCCTAA
ATGGTGATCGACACGTCCGCGCTCGTTGCGATGCTCAGCGACGAGCCAGACGCAGAGCGGTTCGAGGCCGCCGTCGAAGC
CGACCACATCCGGCTGATGTCGACGGCGTCTTACCTGGAAACGGCACTCGTGATAGAAGCCCGCTTCGGTGAACCGGGCG
GACGTGAGCTGGATCTGTGGCTTCATCGCGCCGCGGTCGACCTTGTTGCCGTGCATGCCGACCAAGCGGATGCCGCGCGC
GCCGCCTACCGCACGTACGGCAAGGGAAGGCATCGTGCGGGGCTCAACTACGGCGACTGCTTCTCATACGGCCTCGCCAA
GATCAGCGGCCAGCCACTCCTGTTCAAGGGCGAAGATTTCCAACACACCGACATCGCCACGGTCGCGCTGCCCTAA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8653.71 Da Isoelectric Point: 5.0651
>AT186764 WP_103452516.1 NZ_CP068151:5709104-5709334 [Pseudomonas fluorescens]
MRTVSIFKNGKNQAIRFPNDMAYEGVGELEITRNGDTITLRPVRPSWGSLSELPRADEDFLQKRQDVVGDEGRFNL
MRTVSIFKNGKNQAIRFPNDMAYEGVGELEITRNGDTITLRPVRPSWGSLSELPRADEDFLQKRQDVVGDEGRFNL
Download Length: 231 bp
>AT186764 NZ_CP089772:717797-718051 [Mycobacterium tuberculosis]
ATGGCGCTGAGTATCAAGCACCCGGAAGCCGACCGGCTCGCGCGAGCGCTTGCGGCGCGCACCGGCGAGACGTTGACCGA
GGCAGTGGTTACCGCGTTGCGCGAGCGGCTCGCTCGTGAGACTGGGCGTGCCCGTGTTGTCCCGTTGCGCGACGAGCTTG
CCGCGATTCGGCACCGGTGCGCAGCGTTGCCGGTGGTCGACAACCGGTCCGCTGAGGCGATTCTCGGCTATGACGAGCGC
GGATTGCCGGCCTGA
ATGGCGCTGAGTATCAAGCACCCGGAAGCCGACCGGCTCGCGCGAGCGCTTGCGGCGCGCACCGGCGAGACGTTGACCGA
GGCAGTGGTTACCGCGTTGCGCGAGCGGCTCGCTCGTGAGACTGGGCGTGCCCGTGTTGTCCCGTTGCGCGACGAGCTTG
CCGCGATTCGGCACCGGTGCGCAGCGTTGCCGGTGGTCGACAACCGGTCCGCTGAGGCGATTCTCGGCTATGACGAGCGC
GGATTGCCGGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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