Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 193704..194269 Replicon chromosome
Accession NZ_CP068148
Organism Serratia liquefaciens strain FDAARGOS_1081

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag I6I38_RS00815 Protein ID WP_020837304.1
Coordinates 193704..193982 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag I6I38_RS00820 Protein ID WP_201895934.1
Coordinates 194000..194269 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I38_RS00795 189866..190204 - 339 WP_041415733.1 PTS lactose/cellobiose transporter subunit IIA -
I6I38_RS00800 190562..191131 + 570 WP_020837308.1 peptidylprolyl isomerase A -
I6I38_RS00805 191293..192978 + 1686 WP_046372487.1 sensor histidine kinase -
I6I38_RS00810 192978..193703 + 726 WP_020837306.1 two-component system response regulator BtsR -
I6I38_RS00815 193704..193982 - 279 WP_020837304.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6I38_RS00820 194000..194269 - 270 WP_201895934.1 hypothetical protein Antitoxin
I6I38_RS00825 194495..196021 + 1527 WP_201895935.1 DUF853 family protein -
I6I38_RS00830 196132..196707 + 576 WP_046372490.1 aminodeoxychorismate synthase component II -
I6I38_RS00835 196839..198056 + 1218 WP_020837295.1 aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10374.00 Da        Isoelectric Point: 9.8344

>T186738 WP_020837304.1 NZ_CP068148:c193982-193704 [Serratia liquefaciens]
VKLKWTDPTIADRMAIYDYLASKNPIAAAEIDALISAAASQLSRNPSSGKVGRVSGTREWVIHHFYLLIYEVKNDLLIIL
AVVHSRRQWPKD

Download         Length: 279 bp

>T186738 NZ_CP089768:c4816224-4815841 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10343.66 Da        Isoelectric Point: 6.3758

>AT186738 WP_201895934.1 NZ_CP068148:c194269-194000 [Serratia liquefaciens]
MSESTVVIRVDDELKIAFASAAKAADRTASQLLRDFMRDFVSRQSQQKEYEQWLQVKVDLSRKALQEGRVVDNEDVEAYF
AERRAKSMR

Download         Length: 270 bp

>AT186738 NZ_CP089768:c4816466-4816224 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References