Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4607358..4607503 Replicon chromosome
Accession NZ_CP068139
Organism Klebsiella pneumoniae strain FDAARGOS_1076

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4607394..4607496 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4607358..4607503 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I33_RS22135 4602488..4604548 + 2061 WP_004151449.1 oligopeptidase B -
I6I33_RS22140 4604552..4605211 - 660 WP_021440386.1 exodeoxyribonuclease X -
I6I33_RS22145 4605290..4605520 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6I33_RS22150 4605633..4606007 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6I33_RS22155 4606011..4606880 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
I6I33_RS22160 4606897..4607235 + 339 WP_002911404.1 YebY family protein -
- 4607358..4607503 - 146 - - Antitoxin
- 4607394..4607496 + 103 - - Toxin
I6I33_RS22165 4607871..4608014 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6I33_RS22170 4608119..4609087 - 969 WP_004151446.1 VirK/YbjX family protein -
I6I33_RS22175 4609244..4609897 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
I6I33_RS22180 4609894..4610085 - 192 WP_002911395.1 YebW family protein -
I6I33_RS22185 4610183..4610422 - 240 WP_002911393.1 YebV family protein -
I6I33_RS22190 4610538..4611971 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T186668 NZ_CP068139:4607394-4607496 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT186668 NZ_CP068139:c4607503-4607358 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References