Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 157221..157709 Replicon chromosome
Accession NZ_CP068114
Organism Fusobacterium canifelinum strain FDAARGOS_1126

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6I83_RS00725 Protein ID WP_201627207.1
Coordinates 157221..157484 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6I83_RS00730 Protein ID WP_088389127.1
Coordinates 157485..157709 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I83_RS00690 152459..152962 - 504 WP_201627203.1 hypothetical protein -
I6I83_RS00695 153149..153616 + 468 WP_124797101.1 helix-turn-helix domain-containing protein -
I6I83_RS00700 153567..153992 + 426 WP_198480803.1 ImmA/IrrE family metallo-endopeptidase -
I6I83_RS00705 154041..154400 - 360 Protein_125 HTH domain-containing protein -
I6I83_RS00710 154444..154983 - 540 WP_201627204.1 TlpA family protein disulfide reductase -
I6I83_RS00715 155005..156462 - 1458 WP_201627205.1 HD domain-containing protein -
I6I83_RS00720 156524..157135 - 612 WP_201627206.1 hypothetical protein -
I6I83_RS00725 157221..157484 - 264 WP_201627207.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6I83_RS00730 157485..157709 - 225 WP_088389127.1 hypothetical protein Antitoxin
I6I83_RS00735 157779..159134 - 1356 WP_201627208.1 sodium:alanine symporter family protein -
I6I83_RS00740 159262..160737 - 1476 WP_201627209.1 cobyric acid synthase -
I6I83_RS00745 160881..161132 - 252 WP_201627210.1 hypothetical protein -
I6I83_RS00750 161295..162362 + 1068 WP_201627211.1 NCS2 family permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10545.45 Da        Isoelectric Point: 10.0011

>T186643 WP_201627207.1 NZ_CP068114:c157484-157221 [Fusobacterium canifelinum]
MYKVYFDKKVEKDFKKLDKNVLKLILDWIENNLENIEEPRSKGKALVGNLKDYWKYRIGDYRLITKIDDGKLLIIALELK
HRKEVYK

Download         Length: 264 bp

>T186643 NZ_CP089611:845994-846422 [Mycobacterium tuberculosis]
ATGTTCCTTCTCGACGCCAACGTGCTGCTGGCTGCACACCGCGGTGACCACCCGAATCACCGAACCGTCCGCCCCTGGTT
CGATCGACTGCTCGCGGCTGACGACCCCTTCACAGTGCCGAACCTGGTATGGGCGTCGTTCCTCCGGCTGGCAACGAATC
GACGCATCTTCGAGATTCCGTCACCGCGAGCAGAGGCATTCGCATTCGTCGAAGCCGTCACCGCCCAGCCCCATCACCTT
CCGACGAACCCCGGTCCCAGACACCTCATGCTGCTGCGAAAACTCTGCGACGAGGCCGACGCATCGGGCGACTTGATACC
TGACGCGGTACTCGCGGCCATAGCAGTGGGGCATCACTGCGCCGTGGTGAGCCTGGACAGGGATTTCGCCCGGTTTGCCT
CGGTGCGCCACATTCGCCCGCCGCTCTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8686.02 Da        Isoelectric Point: 5.8834

>AT186643 WP_088389127.1 NZ_CP068114:c157709-157485 [Fusobacterium canifelinum]
MSNITLRLTDEEREILNSVAHLYGDKLSTAIKTILFEKIEEDYNLKIVKDFEKREKENKVELVSLSDFRKKLGV

Download         Length: 225 bp

>AT186643 NZ_CP089611:845713-845970 [Mycobacterium tuberculosis]
ATGCGCACCACGGTGTCAATCTCCGATGAAATACTCGCTGCCGCCAAACGCCGGGCCCGCGAGCGTGGTCAATCGCTGGG
CGCTGTGATCGAGGACGCCCTTCGGCGGGAGTTCGCCGCCGCCCACGTCGGCGGCGCCCGCCCGACCGTCCCGGTTTTCG
ACGGCGGCACCGGTCCGCGGCGAGGCATCGACCTGACCTCGAATAGAGCGTTGTCCGAAGTGCTCGACGAGGGCCTGGAA
CTGAACTCCCGGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References