Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2979623..2979857 Replicon chromosome
Accession NZ_CP068035
Organism Escherichia coli strain U90

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2979624..2979727 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2979623..2979857 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKF55_RS14360 2976535..2977623 + 1089 WP_063100796.1 recombinase RecT -
JKF55_RS14365 2977687..2977881 + 195 WP_021500490.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
JKF55_RS14370 2977874..2978062 + 189 WP_021529595.1 DUF1187 family protein -
- 2977880..2978058 - 179 NuclAT_1 - -
- 2977880..2978058 - 179 NuclAT_1 - -
- 2977880..2978058 - 179 NuclAT_1 - -
- 2977880..2978058 - 179 NuclAT_1 - -
JKF55_RS14375 2978169..2978450 + 282 WP_077248935.1 excisionase -
JKF55_RS14380 2978416..2979492 + 1077 WP_063100794.1 phage integrase Arm DNA-binding domain-containing protein -
- 2979623..2979857 + 235 - - Antitoxin
- 2979624..2979727 - 104 - - Toxin
JKF55_RS14385 2979885..2980226 - 342 WP_000976492.1 YebY family protein -
JKF55_RS14390 2980239..2981111 - 873 WP_000879334.1 copper homeostasis membrane protein CopD -
JKF55_RS14395 2981115..2981489 - 375 WP_000204699.1 CopC domain-containing protein YobA -
JKF55_RS14400 2981628..2981858 + 231 WP_000916763.1 DNA polymerase III subunit theta -
JKF55_RS14405 2981960..2982616 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JKF55_RS14410 2982640..2983302 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2951359..2987267 35908


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T186499 NZ_CP068035:c2979727-2979624 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT186499 NZ_CP068035:2979623-2979857 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References