Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867577..1867722 Replicon chromosome
Accession NZ_CP068033
Organism Klebsiella pneumoniae strain LYS105A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1867613..1867715 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867577..1867722 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKA77_RS09075 1862707..1864767 + 2061 WP_048289976.1 oligopeptidase B -
JKA77_RS09080 1864771..1865430 - 660 WP_002911407.1 exodeoxyribonuclease X -
JKA77_RS09085 1865509..1865739 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JKA77_RS09090 1865852..1866226 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JKA77_RS09095 1866230..1867099 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JKA77_RS09100 1867116..1867454 + 339 WP_016529031.1 YebY family protein -
- 1867577..1867722 - 146 - - Antitoxin
- 1867613..1867715 + 103 - - Toxin
JKA77_RS09105 1868089..1868232 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JKA77_RS09110 1868337..1869305 - 969 WP_004151446.1 VirK/YbjX family protein -
JKA77_RS09115 1869462..1870115 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
JKA77_RS09120 1870112..1870303 - 192 WP_002911395.1 YebW family protein -
JKA77_RS09125 1870401..1870640 - 240 WP_002911393.1 YebV family protein -
JKA77_RS09130 1870756..1872189 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T186473 NZ_CP068033:1867613-1867715 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT186473 NZ_CP068033:c1867722-1867577 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References