Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2084916..2085061 Replicon chromosome
Accession NZ_CP068015
Organism Klebsiella pneumoniae strain 2016_49

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2084952..2085054 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2084916..2085061 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKF56_RS10030 2080046..2082106 + 2061 WP_004151449.1 oligopeptidase B -
JKF56_RS10035 2082110..2082769 - 660 WP_002911407.1 exodeoxyribonuclease X -
JKF56_RS10040 2082848..2083078 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JKF56_RS10045 2083191..2083565 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JKF56_RS10050 2083569..2084438 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
JKF56_RS10055 2084455..2084793 + 339 WP_002911404.1 YebY family protein -
- 2084916..2085061 - 146 - - Antitoxin
- 2084952..2085054 + 103 - - Toxin
JKF56_RS10060 2085429..2085572 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JKF56_RS10065 2085677..2086645 - 969 WP_014907334.1 VirK/YbjX family protein -
JKF56_RS10070 2086802..2087455 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JKF56_RS10075 2087452..2087643 - 192 WP_002911395.1 YebW family protein -
JKF56_RS10080 2087741..2087980 - 240 WP_002911393.1 YebV family protein -
JKF56_RS10085 2088096..2089529 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T186419 NZ_CP068015:2084952-2085054 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT186419 NZ_CP068015:c2085061-2084916 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References