Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 5298252..5298717 Replicon chromosome
Accession NZ_CP067412
Organism Pseudomonas sp. HS6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JJN09_RS24030 Protein ID WP_249484054.1
Coordinates 5298252..5298521 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JJN09_RS24035 Protein ID WP_085613439.1
Coordinates 5298511..5298717 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJN09_RS23990 (JJN09_23960) 5293323..5293796 + 474 WP_249484045.1 type II secretion system protein -
JJN09_RS23995 (JJN09_23965) 5293802..5294176 + 375 WP_096821322.1 type II secretion system protein -
JJN09_RS24000 (JJN09_23970) 5294151..5294702 + 552 WP_249484046.1 type II secretion system protein -
JJN09_RS24005 (JJN09_23975) 5294699..5295091 + 393 WP_249484047.1 curli production assembly/transport protein CsgE -
JJN09_RS24010 (JJN09_23980) 5295088..5295519 + 432 WP_249484049.1 curli assembly protein CsgF -
JJN09_RS24015 (JJN09_23985) 5295549..5296409 + 861 WP_249484050.1 CsgG/HfaB family protein -
JJN09_RS24020 (JJN09_23990) 5297336..5297716 + 381 WP_249484051.1 hypothetical protein -
JJN09_RS24025 (JJN09_23995) 5297788..5297979 + 192 WP_249484052.1 antitoxin -
JJN09_RS24030 (JJN09_24000) 5298252..5298521 - 270 WP_249484054.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JJN09_RS24035 (JJN09_24005) 5298511..5298717 - 207 WP_085613439.1 antitoxin Antitoxin
JJN09_RS24040 (JJN09_24010) 5298988..5300439 - 1452 WP_249484055.1 curlin -
JJN09_RS24045 (JJN09_24015) 5300466..5300930 - 465 WP_249484056.1 curlin -
JJN09_RS24050 (JJN09_24020) 5301035..5303269 - 2235 WP_249484057.1 Ig-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10202.83 Da        Isoelectric Point: 9.4341

>T186298 WP_249484054.1 NZ_CP067412:c5298521-5298252 [Pseudomonas sp. HS6]
MQVEWQPEARAELLHILDYISDRNFKAANKLSNAIEAATIIVAKHPHLYRVGRTPGTREMVVHPNYLLIYQAVGRINILG
VVHARQEYL

Download         Length: 270 bp

>T186298 NZ_CP089315:2182216-2182319 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7569.70 Da        Isoelectric Point: 4.4278

>AT186298 WP_085613439.1 NZ_CP067412:c5298717-5298511 [Pseudomonas sp. HS6]
MIDPSLIDPLCPVVSDLGPEEQAASYDRWLIAKIQASMNDPRPSIPNDQVMAEMHALMEAKRKKYDAG

Download         Length: 207 bp

>AT186298 NZ_CP089315:c2182326-2182158 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References