Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 3257433..3258052 Replicon chromosome
Accession NZ_CP067412
Organism Pseudomonas sp. HS6

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag JJN09_RS14730 Protein ID WP_249490741.1
Coordinates 3257756..3258052 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag JJN09_RS14725 Protein ID WP_249490740.1
Coordinates 3257433..3257753 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJN09_RS14705 (JJN09_14680) 3252840..3254159 - 1320 WP_249490737.1 PAS domain-containing methyl-accepting chemotaxis protein -
JJN09_RS14710 (JJN09_14685) 3254344..3255396 - 1053 WP_249490808.1 diguanylate cyclase -
JJN09_RS14715 (JJN09_14690) 3255544..3256152 - 609 WP_249490738.1 TetR/AcrR family transcriptional regulator -
JJN09_RS14720 (JJN09_14695) 3256368..3257420 + 1053 WP_249490739.1 MBL fold metallo-hydrolase -
JJN09_RS14725 (JJN09_14700) 3257433..3257753 - 321 WP_249490740.1 helix-turn-helix transcriptional regulator Antitoxin
JJN09_RS14730 (JJN09_14705) 3257756..3258052 - 297 WP_249490741.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JJN09_RS14735 (JJN09_14710) 3258152..3258469 - 318 WP_249490742.1 XRE family transcriptional regulator -
JJN09_RS14740 (JJN09_14715) 3258562..3259329 - 768 WP_249490743.1 helix-turn-helix transcriptional regulator -
JJN09_RS14745 (JJN09_14720) 3259442..3260257 + 816 WP_249490744.1 sulfite exporter TauE/SafE family protein -
JJN09_RS14750 (JJN09_14725) 3260348..3261496 + 1149 WP_249490745.1 hypothetical protein -
JJN09_RS14755 (JJN09_14730) 3261623..3262771 + 1149 WP_249490746.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-88)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10734.23 Da        Isoelectric Point: 7.9054

>T186296 WP_249490741.1 NZ_CP067412:c3258052-3257756 [Pseudomonas sp. HS6]
MPTDVQDVFGHALDLAQSGLKHPDAKPLKGFGGAGVLELIEDFDTNTYRAVYTVRFGNAIYVLHCFQKKSTTGIKTAQCD
VDLIRKRLQAAQDHAKGT

Download         Length: 297 bp

>T186296 NZ_CP089315:c57358-57050 [Klebsiella michiganensis]
ATGCAGTATTACGTTTATAAGAATACAGGTCGAATTGCTGCGTATCCTTACCTCCTTGATGTACAGAGTGACATTATCGG
CAAGCGCAATACTCGGGTCGTGATTCCACTGTTTCCACTGAAAAACTATAAAGGCCCACGCGCCGATCGTTTAACACCGC
TTGTCACCGTAGAAGGGGAAGAATACGTCGTGATGACTCACGAACTCGCCAGCATCCCACATCGTGTTCTGGGTAAAGAA
GTTTGTAATCTGAATCACCAGCGCGAAGTCGTTAAAGCTTCAATGGATTTTCTTTTCGACGGGATCTAA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11710.54 Da        Isoelectric Point: 9.0798

>AT186296 WP_249490740.1 NZ_CP067412:c3257753-3257433 [Pseudomonas sp. HS6]
MNEIEESSGNVYQDLGLPNASEMQVKSQLAAKIGEIIKARHLTQSQASEILGLSQPKLSEMLRGKFRGISEAKMMECLSH
LGRDVQIVVKSAPRSRKEGRIEVVFA

Download         Length: 321 bp

>AT186296 NZ_CP089315:c57597-57361 [Klebsiella michiganensis]
ATGCCAGCCGCAAAACGCAATAAGCAGAACGTCAGCGTGACACTGGACCCAGGCCTGGTCAAACAGGCTCGTGAGGTCGG
CATCAATCTGTCTCTAACGTTGACTAACGCTCTAAAAAGCGAAATCCACAGCCTCGAAATAGCCCGCTGGCAAAAAGAAA
ATGCCCAGGCAATCGACTACCTCAATAATTTAACTGAGGAAAATGGACTTCTCTCTGATGAATACAGGACGTTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References