Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 2878467..2879126 Replicon chromosome
Accession NZ_CP067394
Organism Cryobacterium sp. SO1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BJQ95_RS13570 Protein ID WP_130178702.1
Coordinates 2878467..2878862 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BJQ95_RS13575 Protein ID WP_130178701.1
Coordinates 2878875..2879126 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJQ95_RS13550 2873909..2874622 - 714 WP_165385000.1 GntR family transcriptional regulator -
BJQ95_RS13555 2874619..2875497 - 879 WP_130178705.1 carbohydrate ABC transporter permease -
BJQ95_RS13560 2875506..2876384 - 879 WP_130178704.1 sugar ABC transporter permease -
BJQ95_RS13565 2876463..2877761 - 1299 WP_165384999.1 sugar ABC transporter substrate-binding protein -
BJQ95_RS13570 2878467..2878862 - 396 WP_130178702.1 type II toxin-antitoxin system VapC family toxin Toxin
BJQ95_RS13575 2878875..2879126 - 252 WP_130178701.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BJQ95_RS13580 2879218..2879931 - 714 WP_130178700.1 type II CAAX endopeptidase family protein -
BJQ95_RS13585 2880142..2880585 - 444 WP_205750201.1 hypothetical protein -
BJQ95_RS13590 2880708..2881958 - 1251 WP_130178698.1 hypothetical protein -
BJQ95_RS13595 2881998..2882345 - 348 WP_130178697.1 DUF4234 domain-containing protein -
BJQ95_RS13600 2882521..2883453 + 933 WP_130178696.1 NYN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14246.28 Da        Isoelectric Point: 4.5967

>T186239 WP_130178702.1 NZ_CP067394:c2878862-2878467 [Cryobacterium sp. SO1]
VIVYIDTSAVRKLILEEPESTALAQYLDELSARDGVTLVSAALLETELRRLADRTAVSQLAVTDVLRRITLVDIERGSFR
EAGLILPGSSLRSVDALHIAVAVRVATDEFITYDRRQAEAAQSAGLTLVQP

Download         Length: 396 bp

>T186239 NZ_CP089301:c309335-309081 [Novosphingobium kaempferiae]
ATGGATGTGCTCTCGTTCTCCGAAGCGCGCGCCAATTTCAAGGCGCTGATGGATCATGTGGTGGACGATCGTTCGCCCGT
GATCGTCACGCGCCAGAAGGCGGAAGCGGTCGTGATGGTTTCCCTGTCCGACTGGAACGCCATGGCCGAAACCATGCATC
TGCTTTCCACGCCCGCGAACTCGCAGCGGCTCCGCGACGCTGTTCGGGAATTCGATATGGGCGAGGGCGAGGAACACGAT
CTCGTCCAGCCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9127.23 Da        Isoelectric Point: 9.1507

>AT186239 WP_130178701.1 NZ_CP067394:c2879126-2878875 [Cryobacterium sp. SO1]
MKTIPHRELRNNSAEVLRSVQSGESFEVTNNGEVVALLTPPTSAALRGIRFRPQLSRGGFSELTRHSSPQAVGGVLDDLR
EER

Download         Length: 252 bp

>AT186239 NZ_CP089301:c309073-308804 [Novosphingobium kaempferiae]
ATGAAGATCGTCTTCGCTTCCCGCGCCTGGGAAGATTATCAACATTGGGTAGCGAACGATCGCGCGACGCTGGAGCGCCT
AAACGCGCTGGTCGAGCAATGTCGGCACACTCCGTTCAAGGGCACCGGCAAGCCCGAGCCGCTCAAGGGCGAATTGCAGG
GCTGGTGGTCCCGGCGGATCAATCAGGCGGATCGGCTGGTCTATCGTGTCGCGGGCACCGGTGCCGAGCAGCGGCTCGAA
ATCGCGCAATGCCGGTTCCATTACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References