Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 2850050..2850534 Replicon chromosome
Accession NZ_CP067394
Organism Cryobacterium sp. SO1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BJQ95_RS13425 Protein ID WP_130178724.1
Coordinates 2850050..2850316 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag BJQ95_RS13430 Protein ID WP_130178723.1
Coordinates 2850313..2850534 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJQ95_RS13410 2846118..2846387 - 270 WP_130178726.1 hypothetical protein -
BJQ95_RS13415 2846431..2847060 - 630 WP_130178725.1 heme-binding protein -
BJQ95_RS13420 2847617..2849758 - 2142 WP_205750204.1 hypothetical protein -
BJQ95_RS13425 2850050..2850316 - 267 WP_130178724.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BJQ95_RS13430 2850313..2850534 - 222 WP_130178723.1 DUF6290 family protein Antitoxin
BJQ95_RS13435 2850631..2851197 - 567 WP_240694877.1 hypothetical protein -
BJQ95_RS13440 2851392..2852045 + 654 WP_130178722.1 hypothetical protein -
BJQ95_RS13445 2852069..2852269 + 201 WP_130178721.1 hypothetical protein -
BJQ95_RS13450 2852427..2854274 - 1848 WP_130178720.1 iron ABC transporter permease -
BJQ95_RS13455 2854284..2855294 - 1011 WP_130178719.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-86)

Antitoxin

Relaxosome protein TraY

(4-42)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10466.80 Da        Isoelectric Point: 9.9710

>T186237 WP_130178724.1 NZ_CP067394:c2850316-2850050 [Cryobacterium sp. SO1]
VTARWHVETTEQFDRQFRRLDRAVQRRVLTYLEGVEHLDDPRQRGKGLTASHSGVWRYRVGDYRILAQIRDDTMVVLALT
VDHRKDAY

Download         Length: 267 bp

>T186237 NZ_CP089296:314908-315180 [Methylobacterium currus]
ATGAGGCTCACTTTCTCGGACGAAGCCTGGAACGAGTACCTGTTCTGGCAAAGCGAGAGCGAAGCCACGCTGCACCGGAT
CAACGATCTCATCAAAGAGGTCAAACGTACTCCCTTCACGGGAACAGGCGAGCCCGAGCCTTTGAAGTTCAAGCTCGAGG
GGTGGTGGTCGCGCCGGATCTCGGGAGAGCACAGGCTTGTCTATCGCGTGAGCGGTTCCGGCGCGGTCCAGACACTTGAG
ATCGCGCAGTGCCGGTGGCACTACGACGACTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8279.23 Da        Isoelectric Point: 4.6677

>AT186237 WP_130178723.1 NZ_CP067394:c2850534-2850313 [Cryobacterium sp. SO1]
VTISIRLTLDEEERLEKLSQRTGRSKSFYVRAALRAHLTDLEDAFVADEAVDAFEAADRRSRPLSELKAESDL

Download         Length: 222 bp

>AT186237 NZ_CP089296:314630-314911 [Methylobacterium currus]
TTGACGCATGTCAGCCTGACGGAATTGCGCCAGAGCATCGCAACGCATTTCGACCGGGTCGAGCGCGACCGGGAGGAACT
GGTGGTCACCCGCCAGGGCCATGAGCCCCTGGTTCTGCTTCCGCTCGCCGAGTTGGAGAGCTTGCGGGACACCCCTCACC
TCCTCGGTACCCCCGCCAAGGCGCGGCGCCTGATGCGGTCGATCGAACAGCTCGACGCAGGCCGAGGGGTCGAACGCTCG
CCGATCGAACCCGATCAGTCCAAGGACGCAGCCGAGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References