186233

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4614483..4615302 Replicon chromosome
Accession NZ_CP067391
Organism Klebsiella grimontii strain 5512.56

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag JJJ11_RS24100 Protein ID WP_004132607.1
Coordinates 4615045..4615302 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag JJJ11_RS24095 Protein ID WP_154922469.1
Coordinates 4614483..4615034 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJJ11_RS24080 (JJJ11_24070) 4609872..4611269 + 1398 WP_004132593.1 MFS transporter -
JJJ11_RS24085 (JJJ11_24075) 4611393..4612733 + 1341 WP_049085654.1 carbohydrate porin -
JJJ11_RS29700 4612837..4613583 - 747 WP_223226925.1 class I SAM-dependent methyltransferase -
JJJ11_RS29705 4614013..4614369 - 357 Protein_4288 class I SAM-dependent methyltransferase -
JJJ11_RS24095 (JJJ11_24085) 4614483..4615034 - 552 WP_154922469.1 N-acetyltransferase Antitoxin
JJJ11_RS24100 (JJJ11_24090) 4615045..4615302 - 258 WP_004132607.1 YjhX family toxin Toxin
JJJ11_RS24105 (JJJ11_24095) 4615886..4617070 + 1185 WP_049085652.1 mannonate dehydratase -
JJJ11_RS24110 (JJJ11_24100) 4617147..4618622 + 1476 WP_148865109.1 fructuronate reductase -
JJJ11_RS24115 (JJJ11_24105) 4618759..4619535 + 777 WP_116944170.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T186233 WP_004132607.1 NZ_CP067391:c4615302-4615045 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T186233 NZ_CP089283:c259738-259466 [Helicobacter pylori]
ATGCTGACGATTGAAACCAGTAAAAAATTTGATAAGGATCTTAAAATTCTTGTTAAAAATGGGTTTGATTTAAAGCTTTT
GTATAAAGTGGTTGGAAATTTAGCCACAGAGCAACCCCTAGAACCCAAATACAAAGACCACCCACTCAAAGGCGCTTTAA
AAGACTTTAGGGAATGCCACCTAAAACCGGATTTATTGCTTGTCTATCAAATTAAAAAACAAGAAAACACTCTTTTTTTA
GTAAGGCTAGGCAGTCATAGCGAGCTGTTTTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20006.94 Da        Isoelectric Point: 7.2343

>AT186233 WP_154922469.1 NZ_CP067391:c4615034-4614483 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYLAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT186233 NZ_CP089283:c260039-259752 [Helicobacter pylori]
ATGCCTAACACCACCAACAAAGACTACACAAAATACAGCCAAAAACAGCTTTTTAATTTTTTAAATTCTATCAAGGCAAA
GCAAAAAAGAGCGTTAGAAAAATTGAAAGAAATCCAAACTCAAAAGCAAAGGATTAAAAAAGCACTCCAATTTAAAGCGC
TCCATTTAACCGAAAATGGATACACCATAGAAGAAGAGCGAGAAATCTTAGCAAGGGCTAAGGACACTAAGAACCGCCTT
TGTTTTAAAAGCATAGAGGATTTTAAGAAGCATTGTGAAAACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References