Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 827833..828493 Replicon chromosome
Accession NZ_CP067369
Organism Salmonella bongori strain Se40

Toxin (Protein)


Gene name cptA Uniprot ID S5NC56
Locus tag JG560_RS04030 Protein ID WP_000244759.1
Coordinates 828080..828493 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag JG560_RS04025 Protein ID WP_000351186.1
Coordinates 827833..828099 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JG560_RS04005 823830..825263 - 1434 WP_000737109.1 6-phospho-beta-glucosidase -
JG560_RS04010 825421..825732 + 312 WP_015702996.1 N(4)-acetylcytidine aminohydrolase -
JG560_RS04015 825896..826555 + 660 WP_024135108.1 hemolysin III family protein -
JG560_RS04020 826606..827586 - 981 WP_000896119.1 tRNA-modifying protein YgfZ -
JG560_RS04025 827833..828099 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
JG560_RS04030 828080..828493 + 414 WP_000244759.1 protein YgfX Toxin
JG560_RS04035 828545..829066 - 522 WP_001055887.1 flavodoxin FldB -
JG560_RS04040 829179..830075 + 897 WP_000806655.1 site-specific tyrosine recombinase XerD -
JG560_RS04045 830099..830812 + 714 WP_000745612.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JG560_RS04050 830818..832551 + 1734 WP_000813377.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16190.13 Da        Isoelectric Point: 9.4274

>T186163 WP_000244759.1 NZ_CP067369:828080-828493 [Salmonella bongori]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMMLLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGE
DWVLLRPPWLLNSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRVMLQQPLSGQH

Download         Length: 414 bp

>T186163 NZ_CP089236:c3682610-3682329 [Pseudomonas aeruginosa]
ATGACCTATGAGCTGGAGTTCCTGCCCTCAGCCCTGAAGGAGTGGCAGAAGCTCGGCCATACGGTGCGCGAGCAGATCAA
AAAGAAACTGCGCGAGCGCCTGGATAATCCCAAGGTTCAGGCCGACGCCCTCAGGGATATGCCGGGGCACTACAAAATCA
AGCTGCGTGCATCGGGCTATCGCCTGGTATACCGCGTCGAAGATGAGCGCGTGGTGGTCGTGGTGGTTGCCGTTGGCAAG
CGCGAGCGCGGGGCCGCTTACCAATCTGCCAAGGGCCGTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT186163 WP_000351186.1 NZ_CP067369:827833-828099 [Salmonella bongori]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT186163 NZ_CP089236:c3682845-3682600 [Pseudomonas aeruginosa]
ATGCAGAGTATCTTGGCTGACGTCGCTGTCAGCGTTTCTGAGTTGAAGAAAAATCCGTCGGGCATCCTGGCTGGTGCAGG
TGGTATGCCTGTCGCCGTGCTCAACCACAATCGCGTCATGGGATACATGGTGCCGGCAGAGCTCTATGAGCAGATGATGG
AGCGCCTAGATGATCTGGAGTTGGTCGAAATAGTGAAGGCTCGCTCGGGCGAGGAGTCTGTCCCGGTGCGTTTGGATGAC
CTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S5NC56

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References