Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966554..1966698 Replicon chromosome
Accession NZ_CP067261
Organism Klebsiella variicola strain E25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966590..1966692 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966554..1966698 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJB14_RS09575 (JJB14_09575) 1961684..1963744 + 2061 WP_012541258.1 oligopeptidase B -
JJB14_RS09580 (JJB14_09580) 1963748..1964407 - 660 WP_012541259.1 exodeoxyribonuclease X -
JJB14_RS09585 (JJB14_09585) 1964486..1964716 - 231 WP_012541260.1 DNA polymerase III subunit theta -
JJB14_RS09590 (JJB14_09590) 1964830..1965204 + 375 WP_208777824.1 CopC domain-containing protein YobA -
JJB14_RS09595 (JJB14_09595) 1965208..1966077 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
JJB14_RS09600 (JJB14_09600) 1966094..1966432 + 339 WP_008804271.1 YebY family protein -
- 1966554..1966698 - 145 - - Antitoxin
- 1966590..1966692 + 103 - - Toxin
JJB14_RS09605 (JJB14_09605) 1967077..1967220 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
JJB14_RS09610 (JJB14_09610) 1967324..1968313 - 990 WP_032691211.1 VirK/YbjX family protein -
JJB14_RS09615 (JJB14_09615) 1968449..1969102 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
JJB14_RS09620 (JJB14_09620) 1969099..1969290 - 192 WP_002911395.1 YebW family protein -
JJB14_RS09625 (JJB14_09625) 1969388..1969627 - 240 WP_002911393.1 YebV family protein -
JJB14_RS09630 (JJB14_09630) 1969743..1971176 - 1434 WP_077139314.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185961 NZ_CP067261:1966590-1966692 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT185961 NZ_CP067261:c1966698-1966554 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References