Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1962791..1962936 | Replicon | chromosome |
| Accession | NZ_CP067255 | ||
| Organism | Klebsiella pneumoniae strain ESBL_DR09 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1962827..1962929 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1962791..1962936 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JJB15_RS09405 | 1957921..1959981 | + | 2061 | WP_004148850.1 | oligopeptidase B | - |
| JJB15_RS09410 | 1959985..1960644 | - | 660 | WP_032435029.1 | exodeoxyribonuclease X | - |
| JJB15_RS09415 | 1960723..1960953 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JJB15_RS09420 | 1961066..1961440 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JJB15_RS09425 | 1961444..1962313 | + | 870 | WP_032435031.1 | copper homeostasis membrane protein CopD | - |
| JJB15_RS09430 | 1962330..1962668 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1962791..1962936 | - | 146 | - | - | Antitoxin |
| - | 1962827..1962929 | + | 103 | - | - | Toxin |
| JJB15_RS09435 | 1963304..1963447 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JJB15_RS09440 | 1963552..1964520 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| JJB15_RS09445 | 1964677..1965330 | + | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| JJB15_RS09450 | 1965327..1965518 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JJB15_RS09455 | 1965616..1965855 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JJB15_RS09460 | 1965971..1967404 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T185938 NZ_CP067255:1962827-1962929 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT185938 NZ_CP067255:c1962936-1962791 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT