Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1962791..1962936 Replicon chromosome
Accession NZ_CP067255
Organism Klebsiella pneumoniae strain ESBL_DR09

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1962827..1962929 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1962791..1962936 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJB15_RS09405 1957921..1959981 + 2061 WP_004148850.1 oligopeptidase B -
JJB15_RS09410 1959985..1960644 - 660 WP_032435029.1 exodeoxyribonuclease X -
JJB15_RS09415 1960723..1960953 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JJB15_RS09420 1961066..1961440 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JJB15_RS09425 1961444..1962313 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
JJB15_RS09430 1962330..1962668 + 339 WP_002911404.1 YebY family protein -
- 1962791..1962936 - 146 - - Antitoxin
- 1962827..1962929 + 103 - - Toxin
JJB15_RS09435 1963304..1963447 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JJB15_RS09440 1963552..1964520 - 969 WP_004151446.1 VirK/YbjX family protein -
JJB15_RS09445 1964677..1965330 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
JJB15_RS09450 1965327..1965518 - 192 WP_002911395.1 YebW family protein -
JJB15_RS09455 1965616..1965855 - 240 WP_002911393.1 YebV family protein -
JJB15_RS09460 1965971..1967404 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185938 NZ_CP067255:1962827-1962929 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185938 NZ_CP067255:c1962936-1962791 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References