Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2605543..2605814 Replicon chromosome
Accession NZ_CP067250
Organism Escherichia coli strain ESBL_DR28

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2605581..2605684 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2605543..2605814 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJB16_RS12340 2602700..2604139 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JJB16_RS12345 2604257..2604493 + 237 WP_001295499.1 YebV family protein -
JJB16_RS12350 2604598..2604789 + 192 WP_000457842.1 YebW family protein -
JJB16_RS12355 2604790..2605446 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2605543..2605814 + 272 - - Antitoxin
- 2605581..2605684 - 104 - - Toxin
JJB16_RS12360 2605842..2606183 - 342 WP_000976476.1 YebY family protein -
JJB16_RS12365 2606196..2607068 - 873 WP_042346164.1 copper homeostasis membrane protein CopD -
JJB16_RS12370 2607072..2607446 - 375 WP_000168747.1 CopC domain-containing protein YobA -
JJB16_RS12375 2607585..2607815 + 231 WP_000916763.1 DNA polymerase III subunit theta -
JJB16_RS12380 2607917..2608573 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
JJB16_RS12385 2608597..2609259 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T185911 NZ_CP067250:c2605684-2605581 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT185911 NZ_CP067250:2605543-2605814 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References