Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 3785..4320 Replicon plasmid unnamed3
Accession NZ_CP067228
Organism Paracoccus sp. MC1862

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag JGR78_RS17220 Protein ID WP_182805159.1
Coordinates 4072..4320 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag JGR78_RS17215 Protein ID WP_182805205.1
Coordinates 3785..4036 (-) Length 84 a.a.

Genomic Context

JGR78_RS17190JGR78_RS17235JGR78_RS17250JGR78_RS17195JGR78_RS17200JGR78_RS17205JGR78_RS17210JGR78_RS17215JGR78_RS17220JGR78_RS17225JGR78_RS17230JGR78_RS17240JGR78_RS17245
Location: 326..1378 (1053 bp)
Type: Others
Protein ID: WP_182805150.1
Location: 5883..6260 (378 bp)
Type: Others
Protein ID: WP_182805207.1
Location: 8345..9187 (843 bp)
Type: Others
Protein ID: WP_182805171.1
Location: 1385..1735 (351 bp)
Type: Others
Protein ID: WP_182805152.1
Location: 1737..2423 (687 bp)
Type: Others
Protein ID: WP_182805154.1
Location: 2969..3392 (424 bp)
Type: Others
Protein ID: Protein_3
Location: 3392..3646 (255 bp)
Type: Others
Protein ID: WP_182805157.1
Location: 3785..4036 (252 bp)
Type: Antitoxin
Protein ID: WP_182805205.1
Location: 4072..4320 (249 bp)
Type: Toxin
Protein ID: WP_182805159.1
Location: 4354..5142 (789 bp)
Type: Others
Protein ID: WP_200559551.1
Location: 5736..5996 (261 bp)
Type: Others
Protein ID: WP_182805164.1
Location: 7277..7636 (360 bp)
Type: Others
Protein ID: WP_182805166.1
Location: 7633..7857 (225 bp)
Type: Others
Protein ID: WP_182805169.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JGR78_RS17190326..1378+1053WP_182805150.1replication initiator protein A-
JGR78_RS171951385..1735-351WP_182805152.1stability/partitioning determinant-
JGR78_RS172001737..2423-687WP_182805154.1ParA family protein-
JGR78_RS172052969..3392-424Protein_3type II toxin-antitoxin system VapC family toxin-
JGR78_RS172103392..3646-255WP_182805157.1type II toxin-antitoxin system Phd/YefM family antitoxin-
JGR78_RS172153785..4036-252WP_182805205.1BrnA antitoxin family proteinAntitoxin
JGR78_RS172204072..4320-249WP_182805159.1BrnT family toxinToxin
JGR78_RS172254354..5142-789WP_200559551.1hypothetical protein-
JGR78_RS172305736..5996-261WP_182805164.1type II toxin-antitoxin system PemK/MazF family toxin-
JGR78_RS172355883..6260+378WP_182805207.1sugar transferase-
JGR78_RS172407277..7636-360WP_182805166.1type II toxin-antitoxin system VapC family toxin-
JGR78_RS172457633..7857-225WP_182805169.1hypothetical protein-
JGR78_RS172508345..9187+843WP_182805171.1replication initiation protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..5355353553


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-78)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(7-81)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 8917.33 Da        Isoelectric Point: 5.0022

>T185783 WP_182805159.1 NZ_CP067228:c4320-4072 [Paracoccus sp. MC1862]
MLMIVWDEPKRQTNLAKHGLDFADLDEGFFLASLVVPAKDGRNMAIGRLADGTIAVVFATLGTEGVSVISMRPASERERS
LL

Download         Length: 249 bp

>T185783 NZ_CP089030:c104113-103643 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
TTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAACTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8803.93 Da        Isoelectric Point: 6.2815

>AT185783 WP_182805205.1 NZ_CP067228:c4036-3785 [Paracoccus sp. MC1862]
MIASDPDAPEASDDQLAQAKPFTEAFPALAEAMRKNVGGRPKAENPKVAVSLRLDQDVVARFKASGPGWQTRINSALRDA
AGL

Download         Length: 252 bp

>AT185783 NZ_CP089030:c104553-104110 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAATCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCGACCACGTTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAAGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAGACAGGAGCGTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References