Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 66020..66684 Replicon plasmid unnamed1
Accession NZ_CP067226
Organism Paracoccus sp. MC1862

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JGR78_RS16650 Protein ID WP_182806289.1
Coordinates 66020..66427 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JGR78_RS16655 Protein ID WP_182806073.1
Coordinates 66424..66684 (-) Length 87 a.a.

Genomic Context

JGR78_RS16640JGR78_RS16670JGR78_RS16675JGR78_RS16635JGR78_RS16650JGR78_RS16655JGR78_RS16660JGR78_RS16665
Location: 63478..64392 (915 bp)
Type: Others
Protein ID: Protein_59
Location: 68045..69652 (1608 bp)
Type: Others
Protein ID: WP_182806134.1
Location: 70024..71295 (1272 bp)
Type: Others
Protein ID: WP_182806136.1
Location: 61161..63140 (1980 bp)
Type: Others
Protein ID: WP_182806162.1
Location: 66020..66427 (408 bp)
Type: Toxin
Protein ID: WP_182806289.1
Location: 66424..66684 (261 bp)
Type: Antitoxin
Protein ID: WP_182806073.1
Location: 66750..66935 (186 bp)
Type: Others
Protein ID: WP_182806301.1
Location: 67061..67633 (573 bp)
Type: Others
Protein ID: WP_200559529.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JGR78_RS1663561161..63140-1980WP_182806162.1PhoX family phosphatase-
JGR78_RS1664063478..64392+915Protein_59transposase-
JGR78_RS1665066020..66427-408WP_182806289.1type II toxin-antitoxin system VapC family toxinToxin
JGR78_RS1665566424..66684-261WP_182806073.1antitoxinAntitoxin
JGR78_RS1666066750..66935-186WP_182806301.1WGR domain-containing protein-
JGR78_RS1666567061..67633-573WP_200559529.1recombinase family protein-
JGR78_RS1667068045..69652+1608WP_182806134.1AIPR family protein-
JGR78_RS1667570024..71295+1272WP_182806136.1low temperature requirement protein A-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..113686113686


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14709.80 Da        Isoelectric Point: 5.2171

>T185782 WP_182806289.1 NZ_CP067226:c66427-66020 [Paracoccus sp. MC1862]
MIRRLLDTNVVIALVGRRSAELFRRVEASEPGSLAISSIVAHELWYGAYRSQKVAFNLETLRLLFADLAIVDLDPEDARA
AGEIRAELARQGTPIGPYDVLIAGQAKARSLTLVTNNTGEFSRVAGLSLEDWTAA

Download         Length: 408 bp

>T185782 NZ_CP089030:c58138-57827 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9717.90 Da        Isoelectric Point: 5.7066

>AT185782 WP_182806073.1 NZ_CP067226:c66684-66424 [Paracoccus sp. MC1862]
MPHIAKVFRSGNSQAVRLPKDFRLEASEVEISREGDALILRPKLATDRPWASLHAAVERGFSEDFLTSGREQPAEQQRPD
LDQLFS

Download         Length: 261 bp

>AT185782 NZ_CP089030:c57830-57411 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References