Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2576786..2577450 Replicon chromosome
Accession NZ_CP067225
Organism Paracoccus sp. MC1862

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JGR78_RS12665 Protein ID WP_182806075.1
Coordinates 2576786..2577193 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JGR78_RS12670 Protein ID WP_182806073.1
Coordinates 2577190..2577450 (-) Length 87 a.a.

Genomic Context

JGR78_RS12645JGR78_RS12655JGR78_RS12660JGR78_RS12685JGR78_RS12650JGR78_RS12665JGR78_RS12670JGR78_RS12675JGR78_RS12680JGR78_RS12690JGR78_RS12695
Location: 2572416..2572559 (144 bp)
Type: Others
Protein ID: WP_182793555.1
Location: 2574400..2575651 (1252 bp)
Type: Others
Protein ID: Protein_2488
Location: 2575715..2576359 (645 bp)
Type: Others
Protein ID: WP_182793556.1
Location: 2578873..2579482 (610 bp)
Type: Others
Protein ID: Protein_2494
Location: 2573136..2574251 (1116 bp)
Type: Others
Protein ID: WP_200559332.1
Location: 2576786..2577193 (408 bp)
Type: Toxin
Protein ID: WP_182806075.1
Location: 2577190..2577450 (261 bp)
Type: Antitoxin
Protein ID: WP_182806073.1
Location: 2577516..2577701 (186 bp)
Type: Others
Protein ID: WP_182806301.1
Location: 2577827..2578399 (573 bp)
Type: Others
Protein ID: WP_200559333.1
Location: 2579694..2580977 (1284 bp)
Type: Others
Protein ID: WP_200559324.1
Location: 2581085..2581294 (210 bp)
Type: Others
Protein ID: WP_182806145.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JGR78_RS126452572416..2572559+144WP_182793555.1hypothetical protein-
JGR78_RS126502573136..2574251-1116WP_200559332.1asparaginase-
JGR78_RS126552574400..2575651+1252Protein_2488IS3 family transposase-
JGR78_RS126602575715..2576359+645WP_182793556.1hypothetical protein-
JGR78_RS126652576786..2577193-408WP_182806075.1type II toxin-antitoxin system VapC family toxinToxin
JGR78_RS126702577190..2577450-261WP_182806073.1antitoxinAntitoxin
JGR78_RS126752577516..2577701-186WP_182806301.1WGR domain-containing protein-
JGR78_RS126802577827..2578399-573WP_200559333.1recombinase family protein-
JGR78_RS126852578873..2579482+610Protein_2494IS481 family transposase-
JGR78_RS126902579694..2580977-1284WP_200559324.1IS110 family transposase-
JGR78_RS126952581085..2581294-210WP_182806145.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIScluster/Tn--2574555..25809776422


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-44)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14737.89 Da        Isoelectric Point: 5.1976

>T185781 WP_182806075.1 NZ_CP067225:c2577193-2576786 [Paracoccus sp. MC1862]
MIRHLLDTNVVIALVGRRSAELLRRVEASEPGSLAISSIVAHELWYGAYRSQKVAFNLETLRLLFADLAIIDLDPEDARA
AGEIRVELARQGTPIGPYDVLIAGQAKARNLTLVTNNIGEFSRVAGLSLEDWTAA

Download         Length: 408 bp

>T185781 NZ_CP089029:53243-53548 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGACAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGGCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9717.90 Da        Isoelectric Point: 5.7066

>AT185781 WP_182806073.1 NZ_CP067225:c2577450-2577190 [Paracoccus sp. MC1862]
MPHIAKVFRSGNSQAVRLPKDFRLEASEVEISREGDALILRPKLATDRPWASLHAAVERGFSEDFLTSGREQPAEQQRPD
LDQLFS

Download         Length: 261 bp

>AT185781 NZ_CP089029:53023-53241 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References