Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3092011..3092642 Replicon chromosome
Accession NZ_CP067101
Organism Bradyrhizobium diazoefficiens strain 41_2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JJB98_RS14520 Protein ID WP_200454189.1
Coordinates 3092361..3092642 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JJB98_RS14515 Protein ID WP_200454188.1
Coordinates 3092011..3092361 (-) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJB98_RS14505 3087622..3090738 + 3117 WP_200454186.1 CusA/CzcA family heavy metal efflux RND transporter -
JJB98_RS14510 3090742..3091704 - 963 WP_200454187.1 amidohydrolase family protein -
JJB98_RS14515 3092011..3092361 - 351 WP_200454188.1 putative addiction module antidote protein Antitoxin
JJB98_RS14520 3092361..3092642 - 282 WP_200454189.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JJB98_RS14525 3092752..3094149 - 1398 WP_200454190.1 TolC family outer membrane protein -
JJB98_RS14530 3094370..3095149 - 780 WP_200454191.1 enoyl-CoA hydratase -
JJB98_RS14535 3095285..3095932 - 648 WP_200454192.1 hypothetical protein -
JJB98_RS14540 3096225..3096770 + 546 WP_200454193.1 sigma-70 family RNA polymerase sigma factor -
JJB98_RS14545 3096773..3097411 + 639 WP_200454194.1 DUF1109 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(9-89)

Antitoxin

Uncharacterized protein HI1420

(14-101)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10918.46 Da        Isoelectric Point: 10.1808

>T185759 WP_200454189.1 NZ_CP067101:c3092642-3092361 [Bradyrhizobium diazoefficiens]
VRQTRHFSEWLDRLKDANAVARITARIRRMELDNPDDSKNVGRNVREMRIDYGAGYRIYYVQHGTQIMILLCGGDKRTQR
QDIKLAQQLAETL

Download         Length: 282 bp

>T185759 NZ_CP089021:797908-798318 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12304.07 Da        Isoelectric Point: 10.5148

>AT185759 WP_200454188.1 NZ_CP067101:c3092361-3092011 [Bradyrhizobium diazoefficiens]
MPKVVKTTAKTASKTTRFDAADYLDTEERQAAYIAAALETGDADFVRDALGLVARARGMSTIAKKAGLNRESLYKALGET
GNPEFGTVMRIVGALGLTLSAQPATSGRMSKRHRAA

Download         Length: 351 bp

>AT185759 NZ_CP089021:797661-797927 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References